Results 121 to 130 of about 11,608,149 (298)

Teachers’ Professional Development in Context-based Chemistry Education : Strategies to Support Teachers in Developing Domain-specific Expertise [PDF]

open access: yes, 2013
The international trend of redesigning science curricula in terms of meaningful context-based programmes, involves a tremendous change in teachers’ practices.
Freudenthal Institute for Science and Mathematics Education   +3 more
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Construction of acenaphthylenes via C−H activation-based tandem penta- and hexaannulation reactions

open access: yesNature Communications
Acenaphthylene-containing polycyclic aromatic hydrocarbons (AN-PAHs) are noteworthy structural motifs for organic functional materials due to their non-alternant electronic structure, which increases electron affinity.
Jian Li   +6 more
doaj   +1 more source

Prospect Green Map: a community map of environmental, historical, cultural, civic, and recreational sites

open access: yes
A map detailing the sites of interest and importance in the Prospect, NC, and the Robeson County area of North Carolina.
Robeson County Green Map Project
core   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Facile visible-light upcycling of diverse waste plastics using a single organocatalyst with minimal loadings

open access: yesNature Communications
The escalating plastic waste crisis stems from limitations in conventional recycling methods, which are energy-intensive and produce lower-quality materials, leaving a substantial portion unrecycled.
Sijing Zhang   +3 more
doaj   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Conference report: Lake Constance turns green

open access: yes, 2009
Adamova, G.; Ferguson, J.; Ng, S.; Puga Vaca, A.; Rodriguez, H.; Rountree, S.; Seddon, K.... (2009). Conference report: Lake Constance turns green. Green Chemistry. 11(5):604-608. doi:10.1039/b822925mS604608115Horváth, I.
Ng, S.   +7 more
core   +1 more source

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