Results 161 to 170 of about 12,534,618 (262)

Consequences of Mechanical Bonding on the Optical Activity of Cyclo[18]carbon Rings. [PDF]

Chirality
Gustafson A, Sburlati S, Kahr B.
europepmc   +1 more source

Raising the status of chemistry education

, 2004
Despite being one of the cornerstones of science, technology and industry, and forming the foundations of the life sciences, it is apparent that chemistry is in decline internationally as an 'enabling science'. This paper, primarily using Australia as an
Hill, John Orford, Price, William S.
core  

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Tuning CO₂ electroreduction to methane <i>via</i> oxygen termination of M₂BO₂ (M = V, Cr, Hf, Mo, Ta, W) MBene catalysts: a DFT + U investigation. [PDF]

RSC Adv
Ali JM, Obodo KO, Mohammed AM, Mekonnen YS.   +3 more
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

1,2-Diketones as <i>in situ</i> persistent radical precursors: symmetric and unsymmetric diacylation of alkenes under visible light. [PDF]

Chem Sci
Wang J, Guo J, Li CJ, Zeng H.
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Photoinduced Reversible Deformations of Azobenzene-Based Main-Chain Liquid Crystalline Polymer Films. [PDF]

Molecules
Zhang P, Tian G, Wang G, Yu H.
europepmc   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Difunctionalization of unsaturated hydrocarbons via EDA complexes to access pentafluorosulfanyl thioethers. [PDF]

Nat Commun
Zhang X, Jiang Y, Yang HY, Ma Y, Zhang J, Zhang N, Wu G, Sun D, Shi Y, Zhang W, Yue S, Guo S, Wang J.   +12 more
europepmc   +1 more source