Results 51 to 60 of about 2,340,644 (345)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The present work reports the synthesis of multi-wall carbon nanotubes (MWCNTs) over graphite nanosheets by an easy and simple approach without using any external catalyst. Simply, yellow corn seeds were thermally annealed in a hydrogen atmosphere at 1050
E. Duraia, Mikael Opoku, Gary W. Beall
semanticscholar +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Effects of green manure crops on short-term nitrogen availability in organic sweet corn systems : a thesis presented in partial fulfilment of the requirements for the degree of Master of Applied Science in Soil Science [PDF]
In the Gisborne Region of New Zealand (NZ) many organic sweet corn growers use a range of winter green manure crops as a means of maintaining and improving soil fertility, particularly the availability of soil N.
Hanly, J. A. (James Anthony)
core
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Utilization of nitrogen from corn plant residues and green manures by corn [PDF]
A qualidade dos resíduos vegetais de culturas comerciais e adubos verdes influencia a taxa de mineralização/imobilização de N e o respectivo aproveitamento desse nutriente pelas subseqüentes culturas.
BUZETTI, Salatiér +4 more
core +3 more sources
Green Ear Yield in Corn Grown After Cowpea Incorporation
Under irrigation, maize (Zea mays L.) can be grown throughout the year in Northeastern Brazil, which in many areas results in soil degradation. The renewed interest in the study of crop rotations with legumes is targeted at reducing this degradation. The objective of our work was to evaluate the green ear yields of three maize cultivars (AG 8080, AG ...
PAULO SÉRGIO LIMA E SILVA +4 more
openaire +2 more sources
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source

