Results 161 to 170 of about 1,754,507 (309)
Green Extraction at Scale: Hydrodynamic Cavitation for Bioactive Recovery and Protein Functionalization-A Narrative Review. [PDF]
MoleculesMeneguzzo F, Zabini F, Albanese L.
europepmc +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Deep eutectic solvents for green extraction and separation of bioactive compounds from traditional Chinese medicines. [PDF]
Chin MedAli A +5 more
europepmc +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Ultrasound-Assisted Green Extraction and Hydrogel Encapsulation of Polyphenols from Bean Processing Waste. [PDF]
FoodsBosio A, Beccaria M, Lavelli V.
europepmc +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Setting Up a "Green" Extraction Protocol for Bioactive Compounds in Buckwheat Husk. [PDF]
Int J Mol SciSperanza AR +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Lemon Juice-Assisted Green Extraction of Strawberry Enhances Neuroprotective Phytochemicals: Insights into Alzheimer's-Related Pathways. [PDF]
Pharmaceuticals (Basel)Sharaf YM +10 more
europepmc +1 more source