Results 91 to 100 of about 1,067,847 (299)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Technical Feasibility Analysis of Green Energy Storage Options and Hornsea Wind Farms

Energies
The global transition towards clean energy sources is becoming essential to reduce reliance on conventional fuels and mitigate carbon emissions. In the future, the clean energy storage landscape, green hydrogen, and green ammonia (powered by renewable ...
Muhammad Anas Maqbool, Md Jahir Rizvi, Yeaw Chu Lee, Pablo Borja Rosales   +3 more
doaj   +1 more source

New approach for fabrication germanene with Dirac electrons preserved: A first principle study

, 2015
How to obtain germanene with Dirac electrons preserved is still an open challenge. Here we report a sandwich-dehydrogenation approach, i.e., to fabricate germanene through dehydrogenating germanane in a sandwiched structure.
Cao, Juexian, Guo, Zhi-Xin, Li, Ping
core   +1 more source

Strong Anisotropy in Liquid Water upon Librational Excitation using Terahertz Laser Fields

, 2020
Tracking the excitation of water molecules in the homogeneous liquid is challenging due to the ultrafast dissipation of rotational excitation energy through the hydrogen-bonded network.
Adams, Ellen M., Bennett, Kochise C., Colchero, Alejandro, Havenith, Martina, Head-Gordon, Teresa, Hoberg, Claudius, Novelli, Fabio, Ockelmann, Thorsten, Pestana, Luis Ruiz, Ruiz Pestana, Luis, Schwaab, Gerhard, Sebastiani, Federico, Stavrias, Nikolas   +12 more
core   +1 more source

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source

Single-Atom Site Photocatalysts Boosting Organic Synthesis: The Integration of a Metal Active Site and Photosensitive Unit

Nanomaterials
Metallaphotoredox catalysis merges the powerful bond-forming abilities of transition metal catalysis with unique electron or energy transfer pathways accessible in photoexcited states, injecting new vitality into organic synthesis.
Haoyue Sun, Yu Yang, Yanchang Liu, Dongxue Yang, Yichang Liu, Zaicheng Sun   +5 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Strategic route for impending green hydrogen energy in Oman [PDF]

E3S Web of Conferences
Since energy and its sustainability are key global issues, extensive research is currently underway to advance the emerging energy sector. Hydrogen is anticipated to assume a substantial role as a worldwide energy carrier in forthcoming energy frameworks.
Aqeel Ashraf Syed, Rao Ch. Venkateswara, Khan Khaliquzzaman, Mohatram Mohammad, Ahmad Afaq, Jahan Shah, Ramya Ch.   +6 more
doaj   +1 more source

The Formation of IRIS Diagnostics. IX. The Formation of the C I 135.58 Line in the Solar Atmosphere

, 2017
The C I 135.58 line is located in the wavelength range of NASA's Interface Region Imagin Spectrograph (IRIS) small explorer mission. We here study the formation and diagnostic potential of this line by means of non local-thermodynamic-equilibrium ...
Carlsson, Mats, Leenaarts, Jorrit, Lin, Hsiao-Hsuan   +2 more
core   +1 more source