Results 71 to 80 of about 3,729,113 (343)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A Conceptual Approach to Reduce the Product Gas Crossover in Alkaline Electrolyzers

open access: yesMembranes
The crossover of the product gases hydrogen and oxygen in alkaline electrolyzer operation is a critical factor, severely limiting the operational window in terms of current density and pressure.
Diogo Loureiro Martinho, Torsten Berning
doaj   +1 more source

Polymer material innovations for a green hydrogen economy.

open access: yesChemical Communications
Polymeric materials are ubiquitous in modern life. Similar to many other technological applications, polymer materials are essential in advancing the green hydrogen economy, offering solutions for hydrogen production, storage, transport, and utilization.
Satyasankar Jana   +2 more
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Solar–Hydrogen Coupling Hybrid Systems for Green Energy

open access: yes, 2023
Green hydrogen production coupled with solar energy became a universal concept to provide more efficient energy caring for the environment within the 2030 sustainable development goals target.
Balkanlı Ünlü, Esra   +7 more
core   +1 more source

Decarbonizing urban residential communities with green hydrogen systems

open access: yesNature Cities
Community green hydrogen systems, typically consisting of rooftop photovoltaic panels paired with hybrid hydrogen-battery storage, offer urban environments with improved access to clean, on-site energy. However, economically viable pathways for deploying
You Wu, Lexuan Zhong
semanticscholar   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Assessment of the Potential for Green Hydrogen Fuelling of Very Heavy Vehicles in New Zealand

open access: yes, 2021
This study examined the feasibility of green hydrogen as a transport fuel for the very heavy vehicle (VHV) fleet in New Zealand. Green hydrogen is assumed to be produced through water electrolysis using purely renewable energy (RE) as an electricity ...
Rapha Perez, Alan Brent, James Hinkley
core   +1 more source

Effects of a perpendicular ultrasonic field on planar and porous electrodes for hydrogen production in alkaline conditions

open access: yesUltrasonics Sonochemistry
Among water electrolysis systems, alkaline water electrolysers (AWE) are promising for large-scale hydrogen production due to their cost-effective nickel (Ni) electrodes.
Jérémy Gravelle   +4 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

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