Results 81 to 90 of about 457,021 (259)
Traditional energy systems are gradually transitioning to new energy systems dominated by clean sources such as wind, solar, and hydrogen. As the penetration of renewable energy increases, the high uncertainty in their output presents significant ...
Peng Ren +4 more
doaj +1 more source
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Developing efficient, low‐cost, and durable catalysts for the complete dehydrogenation of hydrous hydrazine (N2H4·H2O) remains a significant challenge.
Jianjun Long +6 more
doaj +1 more source
Carbon capture and storage involves CO2 injection into geological structures to mitigate industrial CO2 emissions. CO2 capture processing can lead to inclusion of impurities such as H2S and CH4, which alter the properties of CO2, influencing geochemical ...
Seungmo Ko, Hochang Jang
doaj +1 more source
Acting in accordance with the requirements of the 2015 Paris Agreement, Poland, as well as other European Union countries, have committed to achieving climate neutrality by 2050. One of the solutions to reduce emissions of harmful substances into the environment is the implementation of large-scale hydrogen technologies.
Janusz Kotowicz +2 more
openaire +2 more sources
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Ammonia synthesize through hydrogen produced by green electricity offers an effective solution to the widespread abandonment of wind and solar resources and the shortage of green fuel chemicals.
PEI Changyun +10 more
doaj +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source

