Results 131 to 140 of about 3,729,113 (343)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Palm trees, energy security and green hydrogen futures: Tourists' views on Mallorca's low carbon transition

The development of green hydrogen can provide a welcome boost in energy security, particularly for island nations that may be reliant on energy imports or intermittent renewables as part of their energy transition.
Brennan, Noreen, van Rensburg, Thomas M.
core   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Techno-economic assessment of green hydrogen production integrated with hybrid and organic Rankine cycle (ORC) systems

Heliyon
This study aims to determine the most cost-effective approach for production of green hydrogen, a crucial element for global decarbonization efforts despite its high production costs.
S. Baral, J. Šebo
semanticscholar   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Modeling and Implementation of a Hybrid Green Hydrogen Power System

reservedThis thesis presents the modeling and implementation of a hybrid green hydrogen power system designed for residential use, developed in collaboration with the company Hybitat.
GIACÒ, LORENZO
core  

Hot deformation constitutive modeling of 6111 aluminum alloy linking Z-parameter to the associated microstructural evolution and precipitation strengthening

Journal of Materials Research and Technology
This work investigates the hot deformation behavior and microstructure evolution of 6111 aluminum alloy (core layer in 4343/3003/6111/3003 brazed sheets) via thermal compression (300–500 °C, 0.01–10 s−1). A strain-compensated Arrhenius constitutive model
Minglong Kang, Yunlai Deng, Fei Du, Shuhui Liu, Binhu Wang, Ming-Chun Zhao   +5 more
doaj   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

How Hungary Can Utilize Green Hydrogen for Steelmaking: Insights from Germany

The global pursuit of decarbonization has positioned green hydrogen as a cornerstone of sustainable industrial transformation, particularly in hard-to-abate sectors such as steel production. Green hydrogen, generated via electrolysis powered by renewable
Al Boshi, Alaa
core