Triazine-based corrosion inhibitors: synthesis, significance, and emerging perspectives. [PDF]
RSC AdvShawish I +4 more
europepmc +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Scalable assay to identify inhibitors of prion-like propagation of protein misfolding as potential therapeutics for neurodegeneration. [PDF]
Protein SciNarayan A, Neupane K, Woodside MT.
europepmc +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Green Inhibitors for Prevention of Metal and Alloys Corrosion: An Overview
, 2013 Corrosion control of metal is of technical, economical, environmental and aesthetical importance. The use of inhibitor is the best way to prevent metal and alloys from corrosion. There is an intensive effort underway to develop new plant origin corrosion
Chouhan, JINENDRA SINGH +3 more
core
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Bibliometric analysis of SGLT2 inhibitor treatment for diabetic kidney disease. [PDF]
Ren FailHu D, Chen L, Mai R, Gao T, Guan B.
europepmc +1 more source
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
Green Technologies for a More Sustainable Agriculture
For U.S. agriculture to continue along a sustainable path of economic development, further production increases must be generated by technologies that are both profitable and more environmentally benign. In this context, we assess the role of these green
Vasavada, Utpal +2 more
core
Tuning tRNA synthetase inhibition reveals parabolic induction of stress granules limited in size and RNA content. [PDF]
RNABaymiller M, Helton NS, Dodd B, Moon SL.
europepmc +1 more source