Results 71 to 80 of about 1,327,671 (358)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Improving E-learning mediating green innovation and green technology for green management practice

Discover Sustainability
The development of green technology (GT) and green innovation (GI) in green management practices (GMP) is an important key in today’s digital and sustainable era.
Dewi Nusraningrum, Winda Widyanty, Sonny Indrajaya, Nimit Soonsan, Suphattra Sangthong, Kanyapat Pattanapokinsakul   +5 more
doaj   +1 more source

Board internationalization and green innovation

Economics Letters, 2020
Amid the rapid transition towards a low-carbon world, this study resolves how a nationally-diverse board affects a firm's inclination towards green innovation. Using eleven years (2005-2015) data of all A-share manufacturing companies listed on the Shanghai and Shenzhen stock exchange, we find reliable evidence that board internationalization ...
Usman, Muhammad, Javed, Muzhar, Yin, Junming   +2 more
openaire   +3 more sources

What is green Innovation? A quantitative literature review [PDF]

The importance of green innovation management is growing in practice and academia likewise. To our knowledge, a recent and comprehensive literature review is lacking.
Herstatt, Cornelius, Schiederig, Tim, Tietze, Frank   +2 more
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Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

WITHDRAWN: Green HRM and Green Innovation

, 2023
Abstract We examined the relationships between green transformational leadership, green innovation, and environmental performance via the lens of green human resource management, taking a resource-based perspective and applying the ability-motivation-opportunity hypothesis.
Alexandru Bancea, Jeff Chan, Shawn Cartwright-Johnson, Philip Muszynski   +3 more
openaire   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Do innovation policies and fintech create synergistic effects for the sustainability of urban green innovation?

Sustainable Futures
In light of the increasing global emphasis on environmental sustainability, it is essential to comprehend the synergies between innovation policies and financial technologies in promoting sustainable green innovation.This paper examines the synergistic ...
Cunlin Li, Shiyu Zhang
doaj   +1 more source

Technology innovation & green policy in Korea [PDF]

The new growth engine in the 21stcentury depends on an innovative system to create, distribute and apply knowledge to industrialization processes. The industrial technology has been developed rapidly with the progress of knowledge based information in ...
Kim, Gi Eun
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