Results 41 to 50 of about 21,788 (186)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Specific measures of 'greening' the unemployment insurance system [PDF]
Zbornik Radova Pravnog Fakulteta u Nišu, 2016 The path to the effective protection against unemployment is tiled with a number of normative and practical challenges. Arguing that environmental protection and unemployment protection are challenges which should be addressed together, the author's ...
Janković Jelena
doaj +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Assessing the quality of green jobs: An empirical analysis of French data
International Labour ReviewOur article analyses the quality of green jobs in France, applying a definition of green jobs that has emerged in recent years to the French labour force survey – a large, representative dataset.
doaj +2 more sources
Pest Analysis of Green Jobs in Bulgaria
Икономика и управление на селското стопанство, 2017 Green growth is a form of sustainable development and green jobs support this process. EU outlines plan for maximizing employment opportunities in green sectors and relevant staff in order economy to become “greener”.
CHRISTINA HARIZANOVA, ZORNITCA STOYANOVA
doaj
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
The promotion of both decent and green jobs through cooperatives
Boletín de la Asociación Internacional de Derecho Cooperativo, 2019 Nowadays, it is undeniable that continuous environmental degradation and climate change threaten the sustainability of the planet. As a consequence, there is an urgent need to face these menaces and to promote sustainable development. From this starting
Josune López Rodríguez
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source