Results 41 to 50 of about 723,125 (296)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Characterization of two marker chromosomes in a patient with acute nonlymphocytic leukemia by two-color fluorescence in situ hybridization [PDF]

, 1993
A patient with acute nonlymphocytic leukemia (ANLL), M5b according to French-American-British (FAB) classification, showed monosomy 16, an extra 1p−, and a 21q+. These derivative chromosomes could not be defined by GTG-banding.
Anna Jauch, Brothman, Burke, Christoph Lengauer, Collins, Cooke, Cremer, Cremer, Jauch, Klever, Lengauer, Lengauer, Lengauer, Lichter, Lichter, Marosi, Masafumi Taniwaki, Michael R. Speicher, Moyzis, Pinkel, Pinkel, Rowley, Selleri, Smit, Speleman, Susanne Popp, Thomas Cremer   +26 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Green Libraries As an Active Participant in Environmental Awareness and Ecological Action

Čitalište
In 2015, The United Nations launched the Sustainable Development Agenda 2030, which includes libraries as important contributors to developing nature preservation strategies and enabling the progress of humanity.
Gordana Stojanović, Srđan Gordić, Snežana Miljanović   +2 more
doaj   +1 more source

"Green on the T" Sustainable Habits @BU Libraries Posters [PDF]

, 2019
These posters were created to encourage students to develop sustainable ...
Dong, Angela
core  

Stellar population models at high spectral resolution [PDF]

, 2011
We present new, high-to-intermediate spectral resolution stellar population models, based on four popular libraries of empirical stellar spectra, namely Pickles, ELODIE, STELIB and MILES.
Aihara, Alonso, Alonso, Beifiori, Bessell, Blackwell, Bruzual, C. Maraston, Carney, Cassisi, Cayrel de Strobel, Cayrel de Strobel, Cenarro, Cesetti, Chaboyer, Cimatti, Coelho, Conroy, Davies, De Angeli, di Benedetto, Driver, Eisenstein, Eisenstein, Falcón-Barroso, Fitzpatrick, Fluks, Förster-Schreiber, G. Strömbäck, Girardi, Greggio, Gustafsson, Harris, Heck, Johansson, Kannappan, Katz, Korn, Kroupa, Kurucz, Lançon, Lançon, Le Borgne, Lejeune, Lejeune, Lejeune, Lyubenova, MacArthur, Maraston, Maraston, Maraston, Maraston, Maraston, Maraston, Marigo, Marín-Franch, Mermilliod, Milone, Miner, Peacock, Percival, Pickles, Pickles, Pritzl, Prugniel, Prugniel, Puzia, Renzini, Renzini, Riffel, Riffel, Riffel, Rodríguez-Merino, Saglia, Schaller, Schiavon, Schiavon, Schiavon, Silva, Surma, Sánchez-Blázquez, Thevenin, Thomas, Thomas, Thomas, Thomas, Trager, Tripicco, Vazdekis, Vazdekis, Wake, Walcher, Worthey, Worthey   +93 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Greening the Libraries: A Legislative Gap Analysis of State Library Acts in India

Open Information Science
This study examines the legal framework governing public libraries in India to assess the integration of green library principles into existing legislation.
Diksha, Joshi Abhinav, Dhar Meghna
doaj   +1 more source

Identification of New Drug Candidates Against \u3cem\u3eBorrelia burgdorferi\u3c/em\u3e Using High-Throughput Screening [PDF]

, 2016
Lyme disease is the most common zoonotic bacterial disease in North America. It is estimated that .300,000 cases per annum are reported in USA alone. A total of 10%–20% of patients who have been treated with antibiotic therapy report the recrudescence of
Babar, Mustafeez Mujtaba, Inayathullah, Mohammed, Kim, K. M., Parekh, Mansi B., Pothineni, Venkata Raveendra, Rajadas, Jayakumar, Samineni, A. V., Solow-Cordero, David, Tayebi, Lobat, Wagh, Dhananjay   +9 more
core   +3 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source