Results 31 to 40 of about 4,373 (207)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Mechanism-guided control of intracellular alkalinization and process pH for production of recombinant human B-type natriuretic peptide under the cSAT scheme in Escherichia coli

Microbial Cell Factories
Background Tag-based high-load expression in Escherichia coli can be accompanied by substantial drift of broth and intracellular pH, but mechanistic links between intracellular alkalinization, metabolism and process levers remain unclear. Results Using a
Hang Nie, Yajun Feng, Guanghui Sun, Haijie Li, Jingwen Kang, Yanqing Zhang, Chenhui Zhu, Yu Mi, Yuan Guo, Pei Ma   +9 more
doaj   +1 more source

Precise Optical Modeling of Phosphor-Converted LEDs With Arbitrary Concentration and Thickness Using Bidirectional Scattering Distribution Function

IEEE Photonics Journal, 2018
Phosphor-converted light-emitting diode (pcLED) is one of the most promising methods to generate white light. The interaction of the excitation light with the phosphor in pcLED is a complicated phenomenon, combining light absorption, light conversion ...
Jia-Sheng Li, Yong Tang, Zong-Tao Li, Jia-Xiao Chen, Xin-Rui Ding, Bin-Hai Yu   +5 more
doaj   +1 more source

WS2–WC–WO3 nano-hollow spheres as an efficient and durable catalyst for hydrogen evolution reaction

Nano Convergence, 2021
Transition metal dichalcogenides (TMDs), transition metal carbides (TMCs), and transition metal oxides (TMOs) have been widely investigated for electrocatalytic applications owing to their abundant active sites, high stability, good conductivity, and ...
Tuan Van Nguyen, Ha Huu Do, Mahider Tekalgne, Quyet Van Le, Thang Phan Nguyen, Sung Hyun Hong, Jin Hyuk Cho, Dung Van Dao, Sang Hyun Ahn, Soo Young Kim   +9 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Unveiling the Remarkable Catalytic Performance of Al2O3@Cu‐Ce Core–Shell Nanofiber Catalyst for Carbonyl Sulfide Hydrolysis at Low Temperature

EcoEnergy
Carbonyl sulfide represents a significant organic sulfur impurity in furnace gas, and its removal can enhance the economic value of furnace gas. In this study, a series of Al‐based core–shell nanofiber catalysts were synthesized and employed for the ...
Xin Song, Lina Sun, Panting Gao, Rongji Cui, Weiliang Han, Xiaosheng Huang, Zhicheng Tang   +6 more
doaj   +1 more source

Manufacturing of Bioinspired SS316L-Based Multimaterials: Processing, Mechanical Properties and Modeling

Micromachines
This study presents a hybrid additive manufacturing approach to fabricate bioinspired stainless steel 316L-copper (SS316L-Cu) multimaterial structures using laser powder bed fusion (LPBF).
Vinod Kumar Darapureddy, Tuhin Mukherjee, Sonia Mary Chacko, Zahabul Islam   +3 more
doaj   +1 more source

Facile and Controllable Synthesis of Large-Area Monolayer WS₂ Flakes Based on WO₃ Precursor Drop-Casted Substrates by Chemical Vapor Deposition

Nanomaterials, 2019
Monolayer WS2 (Tungsten Disulfide) with a direct-energy gap and excellent photoluminescence quantum yield at room temperature shows potential applications in optoelectronics.
Biao Shi, Daming Zhou, Shaoxi Fang, Khouloud Djebbi, Shuanglong Feng, Hongquan Zhao, Chaker Tlili, Deqiang Wang   +7 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source