Results 51 to 60 of about 4,373 (207)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

The Manufacturers’ Adoption of Green Manufacturing Under the Government’s Green Subsidy

Sustainability
As environmental degradation intensifies, governments increasingly subsidize green manufacturing to promote sustainability. This study develops a game-theoretic model of two competing supply chains, comprising original equipment manufacturers (OEMs) and both traditional and green contract manufacturers (CMs), to investigate the impacts of subsidies on ...
Wu Chen, Fei Ye, Yao Qiu
openaire   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Hybrid Biocatalysis with Photoelectrocatalysis for Renewable Furan Derivatives’ Valorization: A Review

Photochem
Biocatalysis is fundamental to biological processes and sustainable chemical productions. Over time, the biocatalysis strategy has been widely researched.
Shize Zheng, Xiangshi Liu, Bingqian Guo, Yanou Qi, Xifeng Lv, Bin Wang, Di Cai   +6 more
doaj   +1 more source

Green Manufacturing - An overview

International Journal of Advanced Engineering, Management and Science, 2017
Data on energy consumption, global warming, and carbon di-oxide levels in the environment, industrial pollution, and population is growing extensively which means there are more and more challenges with less sustainability, which leads to think about Green Manufacturing. Consumerism driven consumption in developed countries and population in developing
Snehal Junnarkar, Geetha S, Ujwala Pandharkar, A. J. Parmar, Meera Kokate   +4 more
openaire   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Research Progress on Saccharide Molecule Detection Based on Nanopores

Sensors
Saccharides, being one of the fundamental molecules of life, play essential roles in the physiological and pathological functions of cells. However, their intricate structures pose challenges for detection.
Bohua Yin, Wanyi Xie, Shaoxi Fang, Shixuan He, Wenhao Ma, Liyuan Liang, Yajie Yin, Daming Zhou, Zuobin Wang, Deqiang Wang   +9 more
doaj   +1 more source

Distinguishing Different Cancerous Human Cells by Raman Spectroscopy Based on Discriminant Analysis Methods

Applied Sciences, 2017
An approach to distinguish eight kinds of different human cells by Raman spectroscopy was proposed and demonstrated in this paper. Original spectra of suspension cells in the frequency range of 623~1783 cm−1 were acquired and pre-processed by baseline ...
Mingjie Tang, Liangping Xia, Dongshan Wei, Shihan Yan, Chunlei Du, Hong-Liang Cui   +5 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Effect of double-induced on whey protein isolate nanoparticle formation and stabilized food-grade Pickering emulsions: Stability and gastrointestinal digestion

Food Chemistry: X
The effects of non-heat-induced and double-induced(heat-induced and Na+-induced) whey protein isolate nanoparticles (WPINs) at concentrations of C = 1 %, 2 %, and 5 % as well as oil fractions (φ = 0.1, 0.4, and 0.7) on the properties of food-grade ...
Shenghua He, Yonghui Wang, Guanghui Li, Xueli Gao, Zhiyan Chen, Weiyun Guo, Jihong Huang   +6 more
doaj   +1 more source