Results 91 to 100 of about 1,297,191 (300)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Open-source automatic extraction of Urban Green Space: Application to assessing improvement in green space access [PDF]
ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information SciencesUrban Green Space (UGS) is vital for improving the public health and sustainability of cities. Vector data on UGS such as open data from governments and OpenStreetMap are available for retrieval by interested users, but the availability of UGS data is ...
I. Estacio +4 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The way to Open Access : French strategies to move forward
, 2006 In France, the movement in favour of open access to scientific research output is getting increasingly coordinated and supported at the political level.
Gruttemeier, Herbert
core
Scholarly publishing and open access: searching for understanding of an emerging is phenomenon
, 2007 Scholarly publishing is concerned with the distribution of scholarly information through journals and conferences and other information media. As such scholarly publishing can be understood as a specific part of the information industry.
Kautz, Karlheinz +2 more
core +1 more source
, 2005 Die Umsetzung des Open-Access-Gedankens kann durch Universitätsbibliotheken über die Bereitstellung von »Institutional Repositories« für das so genannte »Self-Archiving« gefördert werden. Wie und in welcher Art und Weise der edoc-Server im Zusammenspiel mit anderen an der Humboldt-Universität betriebenen Publikationsservern die Sichtbarkeit frei ...
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Winning Horizon 2020 with Open Science [PDF]
, 2015 Presentación realizada por Ivo Grigorov en el Winning Horizon2020 with Open Science.
Donnelly, Martin +7 more
core +1 more source
Publications, 2019 This article gives a comprehensive overview of recent Spanish National Research Council (CSIC) publications available in Open Access. With a focus on research articles from the last decade (2008−2018), this work aims to fill the gap in previous ...
Mercedes Baquero-Arribas +2 more
doaj +1 more source