Results 141 to 150 of about 1,297,191 (300)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

DIGITAL.CSIC: Green Open Access at CSIC

open access: yes, 2019
Presentation for EOSC-Synergy Kick off Meeting in Santiago de Compostela, Spain, on September 23-26, 2019.
Bernal, Isabel   +1 more
openaire   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Green Open Access Infographic

open access: yes, 2017
Green Open Access policies can be a tough sell to faculty, especially because of the many myths and misunderstandings about Open Access that can circulate among faculty. This infographic, by means of a Myth vs. Fact approach, seeks to address and correct
Bilby, Dr. Mark
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Freemium Open Access

open access: yes, 2017
Change to 100 % Open Access has been slow. Boselli and Galindo-Rueda found thatapproximately 50–55 % of documents are openly available 3–4 years after publication(Boselli and Galindo-Rueda, 2016) although an industry report estimated that onlyabout a ...
Green, Toby
core  

Open access : un canvi de paradigma per posar a disposició pública el coneixement. El desenvolupament a Alemanya

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2007
La característica principal d'open access és que l'aprofitament del coneixement procedent de l'àmbit d'educació i ciència, que s'ha fet públic i s'ha produït amb fons públics, és lliure (també en el sentit deThe main characteristic of Open Access ...
Kuhlen, Rainer
doaj  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Hybrid gold open access and the Chesire cat’s grin: How to repair the new open access policy of RCUK

open access: yes, 2012
Unintended consequences of RCUK policy mean that if academics want open access publishing, publishers are happy to sell it to them, writes Stevan Harnad.
Harnad, Stevan
core  

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