Results 51 to 60 of about 22,883,037 (247)
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Seit ihrer Gründung im Jahr 1661 ist die Staatsbibliothek zu Berlin (SBB) für die Öffentlichkeit zugänglich. In dieser Tradition sowie im Bewusstsein ihrer besonderen historischen Verantwortung steht die SBB zu ihrer Verpflichtung, wissenschaftliches ...
Staatsbibliothek zu Berlin (5295346) +1 more
core +1 more source
Open Scholarship Practices Reshaping South Africa’s Scholarly Publishing Roadmap
South African higher education institutions are the largest producers of research output on the African continent. Given this status, South African researchers have a moral obligation to share their research output with the rest of the continent via a ...
Reggie Raju, Jaya Raju, Jill Claassen
doaj +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Empfehlungen zur Open-Access-Transformation
Die vorliegenden „Empfehlungen zur Open-Access-Transformation“ wurden von der Ad-hoc-Arbeitsgruppe „Open-Access-Gold“ im Rahmen der Schwerpunktinitiative „Digitale Information“ der Allianz der deutschen Wissenschaftsorganisationen erarbeitet und basieren
Hanig, Kristina +10 more
core +1 more source
Open access in Australia: an odyssey of sorts? [PDF]
Scholarly communication change and open access (OA) initiatives in Australia have followed an Odyssean path in the last decade. The stop-start nature of early initiatives demonstrates that institutional leadership is essential for the successful deposit ...
Colin Steele
core +1 more source
Public Act 098-0295 or the Open Access to Research Articles Act Findings and Recommendations [PDF]
Final report containing the findings and recommendations of Governors State University\u27s Open Access Task Force in compliance with Public Act 098 ...
Open Access Task Force
core +1 more source

