Results 101 to 110 of about 2,452,282 (304)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Kondisi Dan Prospek Pengembangan Eksisting Ruang Terbuka Hijau (RTH) Publik Kota Surakarta [PDF]

, 2017
The existence of green open space continues to decrease as a result of development. Reduction in the quantity of green open space which is very significant in urban areas, causes in lower quality of urban public green open space as a consequence of the ...
Mastuti, A. (Arum), Setiyono, B. (Budi), Turtiantoro, T. (Turtiantoro)   +2 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Desain Pengelolaan Ruang Terbuka Hijau di “Kawasan Sumber Komplek Perkantoran”, Kabupaten Cirebon [PDF]

, 2016
The urban as a civilization and the economy of the public faced with a problem like the degradation of the quality of the environment and over the function of land to be the center of the settlement residents, office complex, the road, shop, and shopping
apriliani, V. (virna), kushandajani, K. (kushandajani), turtiantoro, T. (turtiantoro)   +2 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

How Do Homebuyers Value Different Types of Green Space? [PDF]

It is important to understand tradeoffs in preferences for natural and constructed green space in semi-arid urban areas because these lands compete for scarce water resources.
Bark, Rosalind H., Colby, Bonnie G., Halper, Eve B., Osgood, Daniel E.   +3 more
core   +1 more source

Pengalihfungsian Lahan Ruang Terbuka Hijau (Taman Kota Jalan Garuda Sakti) Menjadi Rumah Sakit Umum Daerah Kota Pekanbaru [PDF]

, 2017
Conversion of green open space (garuda sakti city park) became a regional public hospital of Pekanbaru is a policy taken by the city government to overcome the problem of less than maximal health care to the public.
Kusuma, A. H. (Angga), Sadad, A. (Abdul)
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

EVALUASI DAMPAK PERDA NOMOR 7 TAHUN 2010 TENTANGPENATAAN RUANG TERBUKA HIJAU KOTA SEMARANG (Studi di Kecamatan Candisari Kota Semarang) [PDF]

, 2017
The role of green public space in our urban environment isas an important provider of ecologicalfunctions such as preventing flood, reducing air pollution, and reducing the temperature of the air.The Government of Semarang city publish the local ...
Esra, Oktavia Siahaan
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source