Results 111 to 120 of about 2,333,657 (306)

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Kajian Iklim Mikro Di Bawah Tegakan Ruang Terbuka Hijau Universitas Lampung

Jurnal Sylva Lestari, 2016
University of Lampung has quite extensive green open space with the diversity of vegetation.  The presence of green open space consider to have benefits to control the temperature and humidity.  This research was aimed to know the influence of vegetation
Sapariyanto Sapariyanto, Slamet Budi Yuwono, Melya Riniarti   +2 more
doaj   +1 more source

Faktor-faktor Yang Mempengaruhi Implementasi Kebijakan Ruang Terbuka Hijau Di Kabupaten Rembang [PDF]

, 2015
Environmental imbalance caused as more demand than available land designated as green areas is an important note to Rembang Regency to create policies that focus on how to balance the environment. Green Open Space Policy in Rembang refer to Regulation No.
Miranti, M. (Meidian), Purnaweni, H. (Hartuti), Sundarso, S. (Sundarso)   +2 more
core  

DDF Construction and D-Brane Boundary States in Pure Spinor Formalism

, 2005
Open string boundary conditions for non-BPS D-branes in type II string theories discussed in hep-th/0505157 give rise to two sectors with integer (R sector) and half-integer (NS sector) modes for the combined fermionic matter and bosonic ghost variables ...
C.R. Mafra, J. Polchinski, L. Anguelova, M.B. Green, N. Berkovits, N. Berkovits, N. Berkovits, N. Berkovits, N. Berkovits, N. Berkovits, N. Berkovits, N. Berkovits, N. Berkovits, N. Suryanarayana, O. Bergman, P. Mukhopadhyay, P. Mukhopadhyay, P.A. Grassi, P.A. Grassi, P.S. Howe, Partha Mukhopadhyay, R. Schiappa   +21 more
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

The impact of noise on green open space value

Journal of Environmental Management
I investigate the effect of noise on the amenity value of urban green open spaces in Prague, Czech Republic. First, I use standard hedonic pricing model exploiting cross-sectional and quasi-experimental variation in the apartment price data and then I analyse green open spaces quality inferred from a quantitative spatial model.
openaire   +2 more sources

Tingkat Kualitas Kota Ditinjau Berdasarkan Kebutuhan Luasan Ruang Terbuka Hijau di Kota Depok [PDF]

, 2013
In a way, the city experienced rapid growth due to population dynamics, socioeconomic change, and from the interaction with the other regions. Population growth resulted in the densification of population and settlements rapid and uncontrolled in that ...
Arifien, Y. (Yunus), AT, M. (Mulyadi), Sulastri, M. (Mila)   +2 more
core  

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

The Effectiveness of Building Permit Regulation for Green Open Space at Housing Estates: Case Study of Kendal Regency, Central Java, Indonesia

E3S Web of Conferences, 2018
Increasing demand for settlements steamed by population growth declines the quality of the environment specifically at urban area. The existing spatial planning could not able to prevent the change of land use for settlement and other infrastructures ...
Yulianti Wiwik, Hadi Sudharto P.
doaj   +1 more source

Perancangan Buku Ruang Terbuka Hijau Surabaya dengan Teknik Essay Photography Guna Meningkatkan Kesadaran Lingkungan Hijau Masyarakat Kota Surabaya [PDF]

, 2016
Surabaya can be the learning object to study about how metropolitan city manage their area so that it has the existence of suitable green open space, concerning the fact that it has important role for environment.
Budiardjo, H. (Hardman), Oktaviani, R. (Ria), Yurisma, D. Y. (Dhika)   +2 more
core