Results 121 to 130 of about 2,333,657 (306)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Analisis Ketersediaan Ruang Terbuka Hijau (Rth) Berdasarkan Kebutuhan Oksigen (Studi Kasus : Kota Salatiga) [PDF]

, 2014
Green function in a green open space (RTH) cities as 'lungs' of the city, is one of the aspects of the functioning of recycling, the gas carbon dioxide (CO2) and oxygen (O2).
Hani'ah, H. (Hani'ah), Purwatik, S. (Sri), Sasmito, B. (Bandi)   +2 more
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Urban Spatial Naturalness Degree in the Planning of Ultra-High-Density Cities: The Case of Urban Green Open Spaces in Macau

Buildings
This study deeply examines the livable environment in high-density cities like Macau, focusing on urban green spaces. The study introduces the “urban spatial naturalness degree” indicator, exploring its application with urban population growth and green ...
Jitai Li, Fan Lin, Hongcan Cui, Shuai Yang, Yile Chen   +4 more
doaj   +1 more source

Analisis Spasial Ketersediaan Ruang Terbuka Hijau Terhadap Jumlah Penduduk Di Kota Solo [PDF]

, 2016
According to the regulations of Law No. 26 Year 2007 on Spatial Planning determines that the presentation of green open space in urban areas of at least 30% of the area of the city.
Awaluddin, M. (Moehammad), Hani\u27ah, H. (Hani\u27ah), Rahman, M. D. (Muhammad)   +2 more
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Can urban forests alleviate eye strain? Evidence from eye-tracking metrics

Trees, Forests and People
With the surge in digital screen use, eye strain has become a growing public health concern. While urban forests are known to support psychological and physiological restoration, their capacity to alleviate eye strain remains underexplored.
Yihao Lu, Hui Liu, Bingqing Liu, Han Diao, Jianan Wang   +4 more
doaj   +1 more source

Carbon Sequestration Capability Analysis of Urban Green Space Using Geospatial Data

E3S Web of Conferences, 2018
Indonesia is the world’s sixth largest producer of Carbon Dioxide (CO2) emissions. Jakarta is one of the cities in Indonesia with the highest amount of CO2 emission, due to the growing number of population within the city. Anthropogenic activities in the
Azaria Linda, Wibowo Adi, Putut Ash Shidiq Iqbal, Rokhmatuloh   +3 more
doaj   +1 more source