Results 71 to 80 of about 2,333,657 (306)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Implementasi Penataan Ruang Terbuka Hijau Pada Taman Di Kota Magelang Berdasarkan Perda Nomor 1 Tahun 2014 Tentang Penataan Ruang Terbuka Hijau [PDF]

, 2015
With the new city branding of Magelang as “A City of Million Flowers”, the Local Goverment of Magelang tries to beautify the landscape and appearance of the city through the arrangement of the parks in Magelang City.
Purnaweni, H. (Hartuti), Puspasari, R. S. (Rina), Rengga, A. (Aloysius)   +2 more
core  

Landscape Urban Structure Design - S. Romão Sportive Park, Leiria Polis, Portugal [PDF]

, 2018
It is due to the modern movement the loss of both landscape and open spaces multifunctionality. Consequently, it merges the term of “green spaces” amorphous and residual, often void and without any appropriation, so characteristic of the contemporary ...
Matos, Rute Sousa, Simões, Paula
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Pengembangan Aplikasi Partisipatif Ruang Terbuka Hijau Wilayah Provinsi Jawa Barat

Rekayasa Hijau: Jurnal Teknologi Ramah Lingkungan, 2018
ABSTRAK Proporsi Ruang Terbuka Hijau (RTH) pada suatu wilayah ditargetkan minimal 30% dari luas wilayah kota. Kenyataannya pemerintah kabupaten/kota di Provinsi Jawa Barat belum ada yang dapat memenuhi target tersebut.
- Sumarno, - Indrianawati
doaj   +1 more source

Analisis Ruang Terbuka Hijau Publik di Kabupaten Pringsewu Tahun 2014 [PDF]

, 2016
The purpose of this research was to analyze the availability of the public green open space area on Pringsewu year 2014, with the point of study are: the region size, the public green open space area size and distribution of the public green open space ...
Hidayat, K. (Kiki), Rosana, R. (Rosana), Sri Utami, Rahma Kurnia   +2 more
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

New Urban Governance in Controlling Public Green Open Spaces in Indonesia [PDF]

E3S Web of Conferences
This study aims to describe how new urban governance controls public green open spaces in Indonesia. Cities in Indonesia experience an imbalance of public green open space that must be provided.
Sulistyaningsih Tri, Sunarto, Kulsum Umi
doaj   +1 more source

Implementasi Kebijakan Ruang Terbuka Hijau Privat Di Kecamatan Pedurungan Kota Semarang [PDF]

, 2015
Increasing of using areas can causes the decreasing of green open space availability. Beside that, the decreasing of green open space also caused by judgment that the green open space is reserve area and not economical. To cover up the less area of green
Marom, A. (Aufarul), Purnaweni, H. (Hartuti), Rahmadhani, D. (Dian)   +2 more
core