Results 241 to 250 of about 9,538 (308)

Light‐Promoted Hydrazine Dehydrogenation over Ni/NH2‐MIL‐125: Unraveling Mechanisms for Efficient Hydrogen Production

Advanced Science, EarlyView.
Highly dispersed and electron‐rich Ni nanoparticles (≈2.7 nm) supported on NH2‐MIL‐125 significantly promote the dehydrogenation of hydrous hydrazine under visible‐light irradiation, achieving a turnover frequency of 220.2 h−1 at 323 K, which is more than twice that in the dark (108.1 h−1) and outperforms most reported non‐precious metal catalysts ...
Jianjun Long, Caili Hu, Qilu Yao, Kun Wang, Gang Feng, Shaowen Cao, Zhang‐Hui Lu   +6 more
wiley   +1 more source

Synthesis of triazolo- and tetrazolo-fused 1,4-benzodiazepines via one-pot Ugi-azide and Cu-free click reactions. [PDF]

Beilstein J Org Chem
Ma X, Gao Z, Niu J, Shao W, Yan S, Zhang S, Zhang W.   +6 more
europepmc   +1 more source

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

Advanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian, Sreenidhi Mohanvelu, Sheeja Aravindan, Afsana Parveen Jahir Hussain, Sivasubramani Narayanan, Sabir Salim, Loganayaki Periyasamy, Natarajan Aravindan   +7 more
wiley   +1 more source

Immunoaffinity‐Mimetic Assembly of Peptide‐Aptamer Conjugates and Stem Cell‐Derived Exosomes into Hierarchical Microgels for Spinal Cord Injury Repair

Advanced Science, EarlyView.
Inspired by antibody‐antigen binding, this study develops an unprecedented immunoaffinity‐mimetic assembly strategy, with Peptide‐AptCD63 conjugates acting as antibody surrogates binding CD63 epitopes on mesenchymal stem cell‐derived exosomes. This creates a hierarchical microstructure intended to synergistically integrate antioxidative and anti ...
Dantong Zheng, Yuxin Bai, Zhibo Liu, Zinan Zhao, Yiming Kong, Yao Xu, Qi Jia, Rongrong Zhu, Yong Hu   +8 more
wiley   +1 more source

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source

Curing and Cross-Linking Processes in the Poly(3,3-bis-azidomethyl oxetane)-tetrahydrofuran/Toluene Diisocyanate/Trimethylolpropane System: A Density Functional Theory and Accelerated ReaxFF Molecular Dynamics Investigation. [PDF]

ACS Omega
Qiu C, Chen J, Huan F, Deng S, Yao Z, Wang S, Wang J.   +6 more
europepmc   +1 more source

ACSL1‐Dependent Microglial Lipoimmunometabolic Reprogramming Underlies Cognitive Deficits in Alcohol Use Disorder

Advanced Science, EarlyView.
This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao, Xing‐Rui Cao, Bai‐Qiang Li, Fu‐Ying Zhao, Jia‐Mei Wang, Rui‐Kang Gao, Zhi‐Peng Cao, Zhen‐Xian Du, Hua‐Qin Wang   +8 more
wiley   +1 more source

Thermal Decomposition of Core-Shell-Structured RDX@AlH₃, HMX@AlH₃, and CL-20@AlH₃ Nanoparticles: Reactive Molecular Dynamics Simulations. [PDF]

Nanomaterials (Basel)
Sun Z, Yang L, Li H, Mei M, Ye L, Fan J, Zhu W.   +6 more
europepmc   +1 more source

A gastric retentive robotic capsule enables emergency-prepared and responsive oral drug delivery in canine models. [PDF]

Sci Adv
Huang H, Fan Y, Chen Z, Hu H, Lyu Y, Xu J, Xu J, Wu D, Liang Y, Mao Q, Wang J, Zhang H, Fu H, Guan Y, Chen J, Xu K, Chung HU, Yu X, Nan K.   +18 more
europepmc   +1 more source

An efficient mechanochemical synthesis of alpha-aluminum hydride: Synergistic effect of TiF3 on the crystallization rate and selective formation of alpha-aluminum hydride polymorph [PDF]

, 2019
Cao, Yizheng, Duan, Congwen, Fu, Dong, Hu, Lianxi, Ma, Jinlong, Youngblood, Jeffrey   +5 more
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