Results 91 to 100 of about 1,908,454 (289)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

What factors influence the uptake of GPP (Green Public Procurement) practices? New evidence from an Italian survey [PDF]

open access: yes
Green Public Procurement (GPP) is becoming a cornerstone of environmental policies both at European Union and Member State level. Drawing upon a database of public authorities located in three Italian Regions, this paper assesses the determinants and ...
Marco Frey   +3 more
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Sustainable walking tour of the East Village

open access: yes, 2011
A map of the East Village area of New York City showing sites of interest for sustainability and social innovations.
Green Map System (Firm)
core   +1 more source

A case study investigation on purchasing green transport and logistics services

open access: yes, 2012
n the context of green supply chain management, green purchasing has received increased attention over the past decade and the strategic importance of introducing green aspects into purchasing practices has been recognised.
Isaksson, Karin,   +3 more
core  

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

From Thinking Eco-Labelling and Green Advertising to Buying Green: The Roles of Consumers' Perceptions [PDF]

open access: yesBIO Web of Conferences
Over the past six years, the cosmetics and personal care industry has experienced an average annual growth rate of 9.67%. This growth has resulted in a new challenge, namely the increasing generation of waste each day.
Mazwan M. Zul   +4 more
doaj   +1 more source

Consumer´s purchase intention for a green home

open access: yes, 2021
This thesis aims to explore the factors that influence consumers' intention to purchase a green home in Norway. An online survey was developed where 125 respondents participated. The statistical methods for analysis that were used are descriptive analysis, one-way ANOVA, and linear regression.
Rafiq Ali, Nasima   +1 more
openaire   +2 more sources

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