Results 61 to 70 of about 1,550,778 (354)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Reducing Carbon emissions through transport taxation, GFC Briefing Paper 6 [PDF]
, 2010 Road transport and aviation are, or are becoming, major sources of carbon emissions which will need to be reduced if the UK’s carbon dioxide (CO2) reduction targets are to be met.
Ekins, Paul, Potter, Stephen
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Green Road Construction Technologies in Guangzhou [PDF]
Frontiers of Engineering Management, 2016 Total road pavement in Guangzhou reaches 77 10 6 m 2 . Its huge maintenance and potential rehabilitation calls for a green road system. This paper presents a discussion, first about green road construction technologies together with their applications and development like reclaimed asphalt pavement, rubberized asphalt pavement, and warm mix asphalt ...
Jing-feng Zhang +2 more
openaire +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Green Up Pavement Rehabilitation Design Tool [PDF]
, 2019 While designers produce pavement rehabilitation recommendations every day, for projects of all sizes, most designers have little information on the environmental impact of their recommendations.
Andrei, Dragos +2 more
core +1 more source
Partycypacja w życiu miasta i przeszkody dla mobilności osób starszych w Łodzi [PDF]
, 2017 The article analyzes participation of senior citizens in urban life of Łódź in the context of spending their free time. The paper is also aimed at revealing obstacles for their mobility within the city.
Pielesiak, Iwona
core +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
A novel hierarchical dynamic group decision-based fuzzy ranking approach to evaluate the green road construction suppliers [PDF]
, 2022 Arash Behzadipour +2 more
openalex +1 more source