Results 71 to 80 of about 1,550,778 (354)

Pengalihfungsian Lahan Ruang Terbuka Hijau (Taman Kota Jalan Garuda Sakti) Menjadi Rumah Sakit Umum Daerah Kota Pekanbaru [PDF]

open access: yes, 2017
Conversion of green open space (garuda sakti city park) became a regional public hospital of Pekanbaru is a policy taken by the city government to overcome the problem of less than maximal health care to the public.
Kusuma, A. H. (Angga), Sadad, A. (Abdul)
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Biocontrol and Growth-Promoting Potential of Antagonistic Strain YL84 Against Verticillium dahliae

open access: yesAgronomy
Cotton Verticillium wilt is a disease that significantly impacts the cotton industry, severely affecting cotton quality and the economic well-being of farmers. Bacillus atrophaeus YL84 is a biocontrol bacterium with broad-spectrum antagonistic and growth-
Yuxin Tang   +6 more
doaj   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

Developing Energy Plants for Biofuels Production may Comply to Organic Principles [PDF]

open access: yes, 2008
Biofuels are the only source of renewable environmentally friendly fuel currently suitable for road transport without any negative traits associated with traditional biodiesel or other green energy alternatives.
Akinyemi, Okoro Monday   +1 more
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Jackson, Nell Cartwright (McDaniel), 1888-1974 (SC 2944) [PDF]

open access: yes, 2015
Finding aid only for Manuscripts Small Collection 2944. Letter of Nell (Mrs. Harry G.) Jackson, Bowling Green, Kentucky, to Jane Morningstar, thanking her for an article she wrote for the (Bowling Green) Park City Daily News about “Seeley Shoals,” her ...
Folklife Archives, Manuscripts &
core   +1 more source

Perceived characteristics of the environment associated with active travel: development and testing of a new scale [PDF]

open access: yes, 2008
Background Environmental characteristics may be associated with patterns of physical activity. However, the development of instruments to measure perceived characteristics of the local environment is still at a comparatively early stage, and published ...
Mitchell, R.   +4 more
core   +6 more sources

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