Results 191 to 200 of about 7,744,433 (255)

Standardization of a Protocol to Quantify Benzodiazepines in Human Urine Samples Employing Gas Chromatography-Mass SpectrometryA Green Analytical Chemistry Approach. [PDF]

ACS Omega
Acharya V, Bakkannavar SM, Jain R.
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

A novel green synchronous spectrofluorimetric platform for ultra-trace simultaneous determination of letrozole and bicalutamide in pharmaceutical, biological, and environmental matrices. [PDF]

RSC Adv
Alrashidi AA, Magdy G, Radwan AS.
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Sample Preparation for Glycoproteins

, 2012
Lam, PY, Liu, X, J. Li, Li, J, Chu, IK, M.P.Y. Lam, Lau, E, X. Liu, E. Lau, I.K. Chu   +9 more
core   +1 more source

pH-Regulated Reversible Phase Transition of Natural Deep Eutectic Solvents and Its Application in the Extraction of Fluorinated Liquid Crystal Monomers. [PDF]

J Sep Sci
Shao Y, Jiang X, Jin M, Yang X, Li Z, Liu J.   +5 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

QbD-Assisted RP-HPLC Method Development and Validation for the Quantification of Sotagliflozin With LC-MS/MS Characterization of Its Degradation Products and Greenness Assessment Using AGREE and MoGAPI. [PDF]

Biomed Chromatogr
Gupta A, Sharma A, Devi G, Srujani C, Viswanath A, Madhuri D, Shaik M.   +6 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Low-Cost Preparation of Hydrophobic Silica Aerogels from Water Glass Using Water as the Sole Solvent. [PDF]

Materials (Basel)
Li P, Sun K, Wu Y, Fang Q, Zhang Y.
europepmc   +1 more source