Results 161 to 170 of about 266,217 (267)

Social Policy for Social Work: Placing Social Work in Its Wider Context, Lorraine Green and Karen Clarke [PDF]

British Journal of Social Work, 2016
openaire   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Occupational and psychosocial correlates of sleep disturbance among Chinese expatriate employees in Iraq's Maysan oilfields: a cross-sectional study using regression and network analysis. [PDF]

Front Psychiatry
Liu Z, Li M, Yang C, Zhang C, Gu G, Zhang Y, Liu H, Du J, Fu Y, Han S, Li Q.   +10 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Access at the doorstep: Supporting engagement with movement-based programmes. [PDF]

Soc Sci Med
Tupper E, Pollard T, Atkinson S, Phoenix C.   +3 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Interactive impacts of social deprivation and intranasal oxytocin administration on oxytocin receptor density in prairie vole brains. [PDF]

Front Behav Neurosci
Zheng S, Prounis GS, Ophir AG.
europepmc   +1 more source

From "scientific leadership" to sustainable innovation: the shaping mechanism of talent ecosystem and green innovation capability in Chinese knowledge-intensive firms. [PDF]

Front Psychol
Liang R.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Interventions to promote mental and physical health in changing working environments due to climate change, sustainable work practices, and work in green jobs: The EU INTERCAMBIO project. [PDF]

J Clim Chang Health
Turner MC, Basagaña X, Burdorf A, Canu IG, Gorny A, Kolstad HA, Broberg K, Pronk A, Selander J, Mehlum IS, van Baal P, Svensson S, Pearce N, Scholten B, Godderis L, Straif K, Ghosh M, Viegas S, Albin M, Julvez J, Porcel J, Kogevinas M, INTERCAMBIO Study Group.   +22 more
europepmc   +1 more source