Results 181 to 190 of about 264,624 (301)

Farm-based therapeutic horticulture for people living with dementia: the Vicenza Farm Project. [PDF]

Front Dement
Dalla Costa L, Meneghello F, Righetto C, Senes G.   +3 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Interventions to promote mental and physical health in changing working environments due to climate change, sustainable work practices, and work in green jobs: The EU INTERCAMBIO project. [PDF]

J Clim Chang Health
Turner MC, Basagaña X, Burdorf A, Canu IG, Gorny A, Kolstad HA, Broberg K, Pronk A, Selander J, Mehlum IS, van Baal P, Svensson S, Pearce N, Scholten B, Godderis L, Straif K, Ghosh M, Viegas S, Albin M, Julvez J, Porcel J, Kogevinas M, INTERCAMBIO Study Group.   +22 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Using Social Media to Maximize the Research Impact of Surgeons: Exploratory Linguistic Analysis. [PDF]

JMIR Form Res
Berding S, Green E, Rynarzewska AI, Robinson SS, Royall NA, Jackson T.   +5 more
europepmc   +1 more source

Examining the attitude of Graduate students towards Environment – From a Green Social Work Perspective

, 2021
John Milton, R. Mangaleswaran
openalex   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Are green spaces healthier in spring? Examining seasonal variations in the association between urban green spaces and emotional well-being in Wuhan, China. [PDF]

Front Public Health
Xu Z, Zhang Z, Li B, Wu Y, Jia Y.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source