Results 171 to 180 of about 153,661 (288)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Low-Processed Extracts from Peppermint Leaves (<i>Mentha</i> × <i>piperita</i> L.) as a Source of Polyphenols and Essential Oils: Evaluation of Green Solvents and Valorization of Post-Extraction Plant Material. [PDF]

Molecules
Kowalski R, Kałwa K, Mazurek A, Kowalska G.   +3 more
europepmc   +1 more source

New Screening Protocol for Effective Green Solvents Selection of Benzamide, Salicylamide and Ethenzamide. [PDF]

Molecules, 2022
Przybyłek M, Miernicka A, Nowak M, Cysewski P.   +3 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Thiadiazolobenzotriazole-Based Donor-Acceptor Terpolymers That Can Be Processed from Green Solvents and Deliver 950 nm Emission in Light-Emitting Electrochemical Cells. [PDF]

Chem Mater
Tang S, Filate TT, Genene Z, Kotewicz K, Franco LR, Chen Q, Larsen C, Mammo W, Wang E, Edman L.   +9 more
europepmc   +1 more source

Comparative Study of Bioactive Lipid Extraction from Squid (Doryteuthis gahi) by-Products by Green Solvents. [PDF]

Foods, 2022
Aubourg SP, Trigo M, González MJ, Lois S, Medina I.   +4 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Green Solvents for Eco-friendly Synthesis of Bioactive Heterocyclic Compounds

, 2014
Use of safer solvents satisfies green chemistry practices. From the green chemistry perspective, the best solvent for reactions is no solvent. However, this ideal situation is not always achievable and choice of more eco-friendly solvents becomes ...
Dolzhenko, A., Dolzhenko, Anton
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

The Application of Green Solvents in the Synthesis of S-Heterocyclic Compounds-A Review. [PDF]

Int J Mol Sci
Kosmalski T, Kołodziejska R, Przybysz M, Szeleszczuk Ł, Pawluk H, Mądra-Gackowska K, Studzińska R.   +6 more
europepmc   +1 more source