Results 91 to 100 of about 990,721 (299)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Exponential dichotomies of evolution operators in Banach spaces
, 2014 This paper considers three dichotomy concepts (exponential dichotomy, uniform exponential dichotomy and strong exponential dichotomy) in the general context of non-invertible evolution operators in Banach spaces.
B Sasu +26 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Unification and Planning of Urban Public Spaces With Bioclimatic Conditions. Case Study Drama, Greece [PDF]
The green spaces in the urban environment facilitate the movement of air masses that act as air refreshment in the wider region. The unification of urban open spaces and their enrichment with vegetation affect the micro-climate positively and act as a ...
Julia Georgi, Sophia Sarikou
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Heat kernel and Green function estimates on affine buildings of type $\tilde{A}_r$ [PDF]
, 2006 We obtain a global estimate of the transition density $p^n(0,x)$ associated to a nearest neighbor random walk, called here "simple", on affine buildings of type $\widetilde{A}_r$. Then we deduce a global estimate of the Green function.
Anker, Jean-Philippe +2 more
core +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Regional SustainabilityGreen spaces in urban and suburban areas play a significant role in helping settlements adapt to climate change. The design, quantity, quality, and location of green spaces influence their ability to provide benefits to people and enhance the quality of ...
Tamás Hardi +2 more
doaj +1 more source