Results 121 to 130 of about 167,652 (309)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Value of urban green spaces in promoting healthy living and wellbeing: prospects for planning

open access: yes, 2015
Andrew Chee Keng Lee,1 Hannah C Jordan,1 Jason Horsley2 1Section of Public Health, School of Health and Related Research, University of Sheffield, 2Sheffield City Council, Sheffield, UK Abstract: There has been considerable work done in recent years ...
Lee ACK, Horsley J, Jordan HC
core  

The role of community gardens in achieving UNSDG 11, Target 7: safe, inclusive and accessible green and public spaces

open access: yes
This paper examines the contributions that community gardens can make in achieving Target 7 of UN Sustainable Development Goal (SDG) 11, namely, to ‘provide universal access to safe, inclusive and accessible, green and public spaces’ (UN Citation2021 ...
Howes, Michael, Dolley, Joanne
core   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Planning the Dense and Healthy City for All - Access to Green Spaces in Densification Projects

open access: yes
Enhancing access to urban green spaces is crucial for high-density cities to ensure a healthy and safe urban environment. Densification can be a great opportunity for green space provision in already dense environments.
Verheij, Jessica
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Towards sustainable cities: Evaluating the distribution and functionality of green spaces in Atakum

open access: yesJournal of Design for Resilience in Architecture and Planning
The rapid increase in urbanization has led to a concentration of population and buildings, resulting in reduced green spaces and disrupted ecological balance. This trend negatively affects the well-being and quality of life in cities.
Deniz Yıldız Uslu   +3 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Indicators for managing and planning urban green spaces: a case study in Padova (Northern Italy)

open access: yes, 2018
Sustainable and integrated management of urban green spaces is fundamental for the planning of our cities and towns. Therefore, understanding current conditions and informing citizens on urban green spaces is critical for such sustainable and integrated ...
Martina Penatti   +3 more
core  

Fostering Belonging in Green Spaces

open access: yes
The Leeds City Council Culture Strategy for Leeds 2017-2030 and Leeds Parks & Green Spaces Strategy 2022-32 place green spaces at the core of a vision for a city that offers social cohesion and wellbeing to its residents.
Selim, G.   +6 more
core   +1 more source

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