Results 141 to 150 of about 7,189,249 (350)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Towards sustainable cities: Evaluating the distribution and functionality of green spaces in Atakum

Journal of Design for Resilience in Architecture and Planning
The rapid increase in urbanization has led to a concentration of population and buildings, resulting in reduced green spaces and disrupted ecological balance. This trend negatively affects the well-being and quality of life in cities.
Deniz Yıldız Uslu, Hafith Mohammed Sulayman Almansouri, Amragia H. Mostafa Elahsadi, Mehmet Cetin   +3 more
doaj   +1 more source

Unification and Planning of Urban Public Spaces With Bioclimatic Conditions. Case Study Drama, Greece [PDF]

The green spaces in the urban environment facilitate the movement of air masses that act as air refreshment in the wider region. The unification of urban open spaces and their enrichment with vegetation affect the micro-climate positively and act as a ...
Julia Georgi, Sophia Sarikou
core  

Зеленая архитектура – комфорт в городе [PDF]

, 2016
Sanitary purpose of urban green spaces has been considered. We distinguished different purposes of urban green spaces which depend on positions of it in the urban environment.
Лисина, Е. И., Сродных, Т. Б.   +1 more
core  

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Nature like setting. Cultural ecosystem services and disservices of French urban green spaces [PDF]

, 2016
International audienceSociety has a growing interest for urban nature. The decision-makers have to take this concern into account but they need to know the fallouts of nature for their municipalities, their citizens and the tourists.
Robert, Amélie, Yengué, Jean Louis
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

296 Investing in Community-Led Research Capacity Building: New Seed Grant Type

Journal of Clinical and Translational Science
OBJECTIVES/GOALS: We will describe the community-driven development and impact of the new Community Research Capacity-Building grants from the Alliance for Research in Chicagoland Communities, Northwestern University.
Jen Brown, Claudia Galeno-Sanchez, Corella Payne, Sista Yaa Simpson, Priyanka Reddy, Claudia Galeno-Sanchez, Pedro Serrano   +6 more
doaj   +1 more source

Green Spaces Poster

, 2018
A poster showcasing the effectiveness of green spaces in urban environments on mitigating the urban heat island effect.
openaire   +1 more source