Results 101 to 110 of about 655,110 (257)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Customer involvement in greening the supply chain: An interpretive structural modeling methodology [PDF]

, 2013
The role of customers in green supply chain management needs to be identified and recognized as an important research area. This paper is an attempt to explore the involvement aspect of customers towards greening of the supply chain (SC).
Haleem, Abid, Kumar, Sanjay, Luthra, Sunil   +2 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

A network approach to overcoming barriers to market engagement for SMEs in energy efficiency initiatives such as the Green Deal [PDF]

, 2016
The Green Deal (GD) was launched in 2013 by the UK Government as a market-led scheme to encourage uptake of energy efficiency measures in the UK and create green sector jobs.
Gilmour, Daniel J., O'Keeffe, Juliette, Simpson, Edward   +2 more
core   +3 more sources

Exploring the impact of blockchain technology, green supply chain, green practice, supply chain flexibility on green supply chain performance

Uncertain Supply Chain Management
Changes are occurring in customers demanding that companies produce environmentally friendly products. Apart from that, there is pressure from the government so that companies carrying out business activities can follow the rules and regulations set.
Nelva Kirana Nurafindraningrum, Zeplin Jiwa Husada Tarigan, Hotlan Siagian, Ferry Jie   +3 more
openaire   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Determinants and effects of green supply chain management (GSCM) [PDF]

Green Supply-Chain Management (GSCM) is an increasingly widely-diffused practice among companies that are pursuing environmental excellence. The motivation for the introduction of GSCM may be ethical (e.g.
Fabio Iraldo, Francesco Testa, Nick Johnstone   +2 more
core  

Perancangan Sistem Pengukuran Kinerja Aktivitas Green Supply Chain Management (Gscm) (Studi Kasus: Kud “Batu” [PDF]

, 2014
KUD “BATU” merupakan salah satu sektor industri yang memiliki aktivitas supply chain dalam memproduksi susu pasteurisasi Nandhi Murni. Selama ini, KUD “BATU” belum pernah melakukan pengukuran kinerja supply chain management yang ramah lingkungan.
Fortuna, I. F. (Irvan), Suamtri, Y. (Yeni), Yuniarti, R. (Rahmi)   +2 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

An evaluation of government role in green supply chain management through theories [PDF]

, 2016
Companies self-regulating were mostly for improving their reputation and public image rather than achieving to sustainability goals and this let to shift to co-regulating approach.
Abd Rahman, Azmawani, Fereidouni, Meghdad Abbasian, Nezakati, Hossein   +2 more
core   +2 more sources