Results 111 to 120 of about 4,701,080 (261)
Green supply chain management: uma relação com a visão estratégica de Porter [PDF]
, 2015 TCC (graduação) - Universidade Federal de Santa Catarina. Campus Joinville. Engenharia de Transportes e Logística.O presente trabalho tem por objetivo relacionar os aspectos da gestão da cadeia de suprimentos sustentável com a visão de estratégia ...
Haag, Marina Ferreira Moreira
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Determinants and effects of green supply chain management (GSCM) [PDF]
Green Supply-Chain Management (GSCM) is an increasingly widely-diffused practice among companies that are pursuing environmental excellence. The motivation for the introduction of GSCM may be ethical (e.g.
Nick Johnstone +2 more
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Assessing supply chain performance through the interplay among success drivers
, 2022 This study examines the success drivers of Supply Chain Performance (SCP). This study aims to examine the interrelationships among various proposed success drivers of SCP that were analyzed individually or collectively in some previous studies.
Balfaqih, Hasan
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
, 2021 Reducing anthropogenic carbon emissions and food waste are complex global sustainability challenges that are impacted of and by supply chain activities. This thesis examines structural aspects of the supply chain in relation to sustainable development by
Sundgren, Caroline
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
, 2014 The objective of this paper is to explore the peerreviewed literature on green supply chain practices and green supply chain performance with the intention of characterizing the research methodologies used in these areas of research.
Gandhi, Asif
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source