Results 71 to 80 of about 10,808 (211)

Exercise limitations in amyloid cardiomyopathy assessed by cardiopulmonary exercise testing—A multicentre study

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1326-1335, April 2025.
Abstract Aims Amyloid cardiomyopathy is caused by the deposition of light chain (AL) or transthyretin amyloid (ATTR) fibrils, that leads to a restrictive cardiomyopathy, often resulting in heart failure (HF) with preserved or reduced ejection fraction.
Robin Willixhofer   +25 more
wiley   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

open access: yesEpilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang   +3 more
wiley   +1 more source

Ketogenic diet for infantile epileptic spasms

open access: yesEpilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury   +3 more
wiley   +1 more source

Turning the TIDE: Paediatric Provider Perspectives on Implementing a Transition Intervention for Eating Disorders

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Objective This qualitative study aimed to explore paediatric providers' perspectives on the acceptability, feasibility, and appropriateness of the Transition Intervention for Eating Disorders (TIDE) within existing specialised paediatric eating disorder (ED) programs to inform its refinement and implementation in real‐world clinical settings ...
Maria Nicula   +3 more
wiley   +1 more source

Hybrid Simulation–Machine Learning Surrogates for Coordinate‐Based Solar and Wind Energy Yield Assessment in Iraq: A Streamlit Decision‐Support Tool

open access: yesEnergy Science &Engineering, EarlyView.
This study integrates climatic simulations with machine learning to predict solar and wind energy across Iraq. Results show Random Forest excels for solar (R2 = 0.98) and neural networks for wind (R2 = 0.97), enabling a practical web tool for renewable energy planning. ABSTRACT Driven by the global shift away from fossil fuels, solar and wind resources
Bassam Musheer Kareem   +3 more
wiley   +1 more source

Integrated Solar and Wind Energy Systems for Domestic Power Generation and CO2 Emissions Reduction

open access: yesEnergy Science &Engineering, EarlyView.
A well‐structured and sequentially methodical procedure for evaluating the Wind and Photovoltaic Hybrid Energy System‐based technical, environmental, and economic viability. This study investigates the integration of solar photovoltaic(PV) and wind energy systems for domestic electricity generation in the Gaza Strip.
Mohamed Elnaggar   +9 more
wiley   +1 more source

Dexmedetomidine infusions improve cardiovascular and renal function in anaesthetised, experimentally endotoxaemic horses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Dexmedetomidine infusions are beneficial in anaesthetised endotoxaemic horses when administered concurrent to endotoxin, but post‐conditioning effects are unknown. Objectives To evaluate whether a dexmedetomidine infusion is beneficial in horses administered Escherichia coli O55:B5 lipopolysaccharides (LPS) endotoxin prior to ...
Sera Lee   +4 more
wiley   +1 more source

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