Mepce Restrains Ferroptosis in Prostate Cancer Through 7SK–P‐TEFb Pause Control
Advanced Science, EarlyView.Genome‐wide CRISPR screening identifies MEPCE as a pause‐control regulator that restrains ferroptosis in prostate cancer. MEPCE loss releases P‐TEFb/CDK9 from 7SK snRNP control, enhances RNAPII Ser2 phosphorylation, and accelerates NRF2‐HMOX1‐driven labile iron accumulation and lipid peroxidation, revealing a transcriptional kinetic gate that lowers ...
Tongtong Zhang +9 more
wiley +1 more source
Entrepreneurship and Economic Growth: An Investigation into the Relationship between Entrepreneurship and Total Factor Productivity Growth in the EU [PDF]
Endogenous growth theory assigns an important role for entrepreneurship in the process of economic development. This paper sets to formally test the impact of entrepreneurship on economic growth.
Andrzej P. Dabkowski
core
Advanced Science, EarlyView.Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem +24 more
wiley +1 more source
Green Total Factor Productivity Growth: Policy-Guided or Market-Driven? [PDF]
Int J Environ Res Public Health, 2022 Wang S, Yang C, Li Z.
europepmc +1 more source
Returns to Scale, Technical Progress and Total Factor Productivity Growth in New Zealand Industries [PDF]
This paper reviews and applies some recently proposed methods for separating total factor productivity (TFP) growth into contributions from technical progress and returns to scale, allowing for imperfectly competitive markets.
Kevin J Fox
core
Perceived Time Shapes Physical Fatigue Accumulation and Its Neural Oscillatory Correlates
Advanced Science, EarlyView.Can a clock change the course of physical fatigue? By covertly manipulating the clock calibration during repeated isometric contractions, we showed that perceived time shapes fatigue accumulation and frontal oscillatory dynamics. While fatigue accumulation was only reduced when the clock was slowed down, frontal oscillatory dynamics followed perceived ...
Pierre‐Marie Matta +3 more
wiley +1 more source
Measurement of China's Green Total Factor Productivity Introducing Human Capital Composition. [PDF]
Int J Environ Res Public Health, 2022 Cheng C, Yu X, Hu H, Su Z, Zhang S.
europepmc +1 more source
Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies
Advanced Science, EarlyView.This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan +5 more
wiley +1 more source
Exploring the Mechanism of the Impact of Green Finance and Digital Economy on China's Green Total Factor Productivity. [PDF]
Int J Environ Res Public Health, 2022 Guo J, Zhang K, Liu K.
europepmc +1 more source
The contribution of innovations in total factor productivity of organic olive enterprises [PDF]
This paper measures the contribution of innovations in total factor productivity(TFP) of organic olive farmers. By constructing an innovation variable instead of the use of a time trend, technical change is replaced by technical difference and TFP growth
Papanagiotou, Evangelos +1 more
core