Results 101 to 110 of about 590,091 (260)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Paving the Way for a Green Transition in the Design of Sensors and Biosensors for the Detection of Volatile Organic Compounds (VOCs). [PDF]
Biosensors (Basel), 2022 Cova CM +4 more
europepmc +1 more source
FEBS Letters, EarlyView.Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
The Implementation of the European Pillar of Social Rights in the Era of Polycrisis
Social InclusionThis thematic issue focuses on the implementation of the European Pillar of Social Rights (EPSR) amid a context of polycrisis. It examines how overlapping global disruptions such as the Covid‐19 pandemic or current geopolitical instability have shaped ...
Francisco Simões +2 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Electromobility as a State programme?
Revue de la Régulation: Recent regulation theory inspired studies have observed a re-orientation in the German governments’ industrial strategy toward a more activist state despite opposition of German industry. By highlighting a critical tension between politics and industry,
Nathan Weis
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
A green and equitable transition
In this booklet from EPI•STEM National Centre for STEM Education, School of Education, University of Limerick, we want to share ideas and resources for getting ahead with the STEAM Education partnership project we are offering schools in Limerick in collaboration with the Hunt Museum and the Limerick Education Support Centre.
Mooney Simmie, Geraldine +1 more
openaire +2 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
This report examines the interrelationship between green energy transition, energy security, and energy poverty in selected countries of the Western Balkans (WB) and Eastern Partnership (EaP), namely Serbia, Bosnia and Herzegovina, Kosovo, Moldova, and Ukraine.
Prodromidou, Alexandra +2 more
openaire +1 more source