Results 81 to 90 of about 615,963 (259)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Hidden Dimensions of Injustice in the Green Transition of China’s Coal Mining Industry
Social InclusionThe social impact of China’s policy of phasing out excess coal production since the 2010s is examined through the lens of “just transition.” Qualitative fieldwork undertaken in Liupanshui, Guizhou province, focussed on seven mines, among which three were
Guanli Zhang, Bingyi Zhang
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
EconomiesGiven the need to strengthen responses to the growing challenges posed by climate change, the purpose of this paper is to explore innovative approaches and interdisciplinary perspectives for tackling these issues, focusing on the role of the ...
Antonios Angelakis +2 more
doaj +1 more source
Twin Transitions - Digital and Green Transitions
, 2023 The "twin transitions" have become more current than the "twin deficits." The number one theme of sustainable development today is the double transition – green and digital transition. Discussions and debates about their contribution to the economy, sustainable development, circular economy, the environment, and the social community are already well ...
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The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Administrative SciencesThis research aims to examine the relationship between green finance, fintech, and sustainable development. PRISMA and bibliometric analyses were conducted to determine the most important trends related to this subject.
Georgia Zournatzidou
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Shaping tomorrows: the CCS as agents of change in Europe’s transition
Frontiers in CommunicationThis article explores the role of the Cultural and Creative Sectors (CCS) as systemic enablers of the European Union’s (EU) triple transition—green, digital and just.
Eva De Smedt, Isabelle De Voldere
doaj +1 more source