Results 61 to 70 of about 615,963 (259)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Ecology for the rich? Class aspects of the green transition and the threat of right-wing populism as a reaction to its costs in Poland

Sustainability: Science, Practice, & Policy
This article sheds light on the class determinants of ecological attitudes and, at the same time, tries to emphasize the general importance of class differentiation for the implementation of sustainable development policies.
Piotr Żuk, Paweł Żuk
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Sustainable management in companies and green transition consequences based on the Polish energy sector in 2014-2024

Zeszyty Naukowe Wyższej Szkoły Finansów i Prawa w Bielsku-Białej
Sustainable management in the Polish energy sector in 2014–2024 plays a key role in the transformation process towards the development of green energy.
Joanna Toborek- Mazur, Karol Partacz
doaj   +1 more source

Just Green Transitions - An Introduction

Abstract Just Green Transitions (JGTs) address the shift to sustainable, low-carbon economies while ensuring fairness and inclusivity. Central to global policies like the Paris Agreement and the European Green Deal, JGTs remain multidimensional, diverse, and complex in their interpretation and application.
Erblin Berisha, John Moodie, Ledio Allkja, Marija Jeftić   +3 more
openaire   +2 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Arguments for a Community-Based Approach to Geothermal Energy Development

Energies
This paper investigates the theoretical foundation for developing renewable geothermal resources locally. For this reason, we pay attention to the role of communities in geothermal development. We derive it from the integral characteristics of geothermal
Katarzyna A. Kurek, Johan van Ophem, Jacek Strojny   +2 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Policy Uncertainty and Investment Dynamics in the Renewable Energy Sector: A Post-Pandemic Perspective from Romania [PDF]

Management and Economics Review
This article investigates the influence of policy uncertainty on investment decisions in Romania’s renewable energy sector during the post-COVID-19 period.
Mihai SANDU, Mihai VRISCU, Ahmed SHAKIR
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source