Results 151 to 160 of about 17,645 (300)

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Association and Interaction of Neighborhood Environment and Social Factors With Blood Glucose Among Adult Residents: A Cross-Sectional Study. [PDF]

Health Sci Rep
Zhang XJ, Xianyu Y, He T, Zhang G, Cui J, Cheng YX, Liu YJ, Chen J, Liu Q, Luo D, Wang XQ, Yang BX, Zou H.   +12 more
europepmc   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

The History and Present of Greenery Accompanying Road Network

, 2015
This thesis focuses on the accompanying greenery of road network in general and on its historical development. Accompanying greenery of road network is mainly represented by alleys and avenues.
DUŠEK, Jiří
core  

Linking Children's Emotional Experiences of Space with Health-Oriented Urban Design: Towards School Streets in Belgrade. [PDF]

Int J Environ Res Public Health
Vukmirović M.
europepmc   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Systemic approach to green infrastructure and nature-based solutions uptake: Insights from the Polish cities. [PDF]

Ambio
Zwierzchowska I, Stępniewska M, Wolszczak G.   +2 more
europepmc   +1 more source

Greenery in urban morphology

The understanding of urban social-ecological systems requires integrated and interdisciplinary methods. This paper explores differences in the accessibility of urban green spaces (UGS) based on urban morphology. In contrast to other comparative analyses that followed simplified quantification of UGS provision and/or omitted the impact of morphological ...
Łaszkiewicz, Edyta, Wolff, Manuel||, Andersson, Erik||, Kronenberg, Jakub||, Barton, David N., Haase, Dagmar||, Langemeyer, Johannes||, Baró Porras, Francesc||, McPhearson, Timon||   +8 more
openaire   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Greenery in public space

Tématem mé bakalářské práce je Zeleň ve veřejném prostoru. Má práce obsahuje teoretickou a praktickou část, kde v rámci teoretické části rozeberu veřejný prostor a především pak veřejnou zeleň. V praktické části zpracuji a vyhodnotím 20 otázek položených
Nováková, Lenka
core