Results 41 to 50 of about 17,645 (300)
Acta Agrobotanica, 2014 Rosa gallica is a native species under strict protection and its cultivars are practically unknown in Poland. The aim of the observations was to evaluate the possibilities of growing the studied cultivars in the climate of Central Poland.
Marta J. Monder
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Urban greenery and mental wellbeing in adults: Cross-sectional mediation analyses on multiple pathways across different greenery measures [PDF]
, 2019 BACKGROUND: Multiple mechanisms have been proposed to explain how greenery in the vicinity of people's homes enhances their mental health and wellbeing.
Liu, Y +7 more
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Effect of the Existence of Brownfields on Selected Item Expenditure of Municipal Budgets
Transactions of the VŠB: Technical University of Ostrava, Civil Engineering Series, 2017 The existence of brownfields in an area results in a number of problems. Among others, economic problems are often mentioned. They are mainly connected with negative influence on urban economics, i.e.
Endel Stanislav +2 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Urbanistinių struktūrų potencialo vertinimas: Kauno centras miesto visumos kontekste
Journal of Architecture and Urbanism, 2011 The regenerative potential of a city as an ever- changing complex system is revealed by the evaluation results of the potentials of its subsystems. To reach this aim, method of fractal analysis can be used, which not only reveals the form properties of ...
Kęstutis Zaleckis +1 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source