Results 61 to 70 of about 60,764 (306)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Evaluation of growth and flowering of cultivars derived from the rugosa (Rosa rugosa Thunb.) growing in the national collection of rose cultivars in the Polish Academy of Sciences Botanical Garden in Powsin. Part I. The historical cultivars

Acta Agrobotanica, 2012
In the years 2000-2011, observations were made of shrubs of the cultivars derived from the Rugosa (R. rugosa Thunb.) gathered in the Collection of Rose Cultivars of the Polish Academy of Sciences (PAS) Botanical Garden – Center for Biological Diversity ...
Marta J. Monder
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Assessing visual quality parameters in urban streetscape along transit corridors [PDF]

Urbanism. Arhitectura. Constructii
With the world’s rapid urban development, it has been observed that space for sociability has decreased. To overcome the impact of the same, streets should develop as an urban space along transit corridors.
Manika Goel, Amit Hajela, Safiulllah Khan   +2 more
doaj  

Influence of management practices on quality and biodiversity of tomatoes in Germany [PDF]

, 2005
Four old and endangered tomato cultivars were cultivated under greenhouse conditions with different levels of organic N-fertilisation and harvest at different maturity stages in order to develop a conclusive concept to preserve the diversity of old ...
Klein, Daniela, Koepke, Ulrich, Kumar, Ramesh   +2 more
core  

Exploratory Fieldwork on Balconies as Threshold Spaces on the Juliusz Słowacki housing estate in Lublin [PDF]

, 2019
The author reflects upon her experience of exploratory fieldwork conducted by an interdisciplinary group during the Urban Summer School. The research was conducted within an environment built according to the idea of "Open Form", introduced by architect ...
Otrishchenko, Natalia
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Nature in Indoor Environments: An EEG Study Comparing Natural Greenery with Nature-Derived Visual Alternatives

Buildings
Integrating greenery into built environments plays a significant role in enhancing indoor space, nurturing mental health, and reinforcing overall well-being.
Dea Luma, Yoshiyuki Kawazoe
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source