Results 91 to 100 of about 181,465 (294)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
People and NatureIndigenous peoples' deep time relationships with ecosystems hold valuable lessons on how humans can relate to, and be stewards in, the natural world. At the crux of these lessons is the multifaceted way Indigenous peoples participate within ecosystems ...
Spencer Greening (La’goot)
doaj +1 more source
Yield gap and the shares of climate and crop management in yield and yield variability of staple crops in West Africa. [O-3330b-01] [PDF]
, 2015 " Yield gap " (Yg) is a key concept of agricultural science for identifying the room for improvement of yields through better management of the agroecosystem. in rainfed agriculture Yg is the difference between actual yield (Ya) and the theoretical water
Affholder, François +4 more
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
, 2013 Studies of rare decays are an indirect probe of New Physics (NP). This document presents recent measurements of rare decays in the charm sector by the LHCb experiment.
Greening, Ed
core
GREENING PRACTICE IN OVERBURDEN ROCK DUMPS OF THE IRON ORE QUARRIES IN KRYVYI RIH [PDF]
, 2018 At the territory of Kryvyi Rih, where from the end of the 20th century iron ore mining was performed in the open way, and in the following decades by underground method, dozens of decommissioned dumps and those in which the ...
Korshykov, Ivan, Krasnoshtan, Oleh
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Green3: A green extraction of green additives for green plastics
HeliyonPLA/PBAT bioplastic is a commercial biodegradable plastic employed for packaging and several food and agriculture applications. In this regard, properties such as the antioxidant ability to extend food shelf life and light resistance, are of great interest in the production of packaging and mulching films, respectively.
Vera Muccilli +8 more
openaire +4 more sources
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source