Results 101 to 110 of about 368,089 (290)
Records of the Australian Anti-Metric Association
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Australian Anti-Metric Association
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Salmon abundance and patterns of forest greenness as measured by satellite imagery
Linkages across ecosystems can shape productivity. Salmon carcasses are exemplary of cross-system linkages, because they can fertilize riparian vegetation and shape patterns of terrestrial biodiversity.
Hocking, Morgan D +3 more
core +1 more source
Nanotechnology is the field of science that has achieved remarkable advances over the past few decades, enabling significant developments in biomedical, chemical, and environmental applications. The rapid expansion of nanomaterial research has led to the
Rehab H. Elattar +5 more
doaj +1 more source
Effects of long-term rainfall decline on the structure and functioning of Hawaiian forests
Climate change is altering the dynamics of terrestrial vegetation, with consequences for the functioning of Earth’s biomes and the provisioning of ecosystem services.
Jomar M Barbosa, Gregory P Asner
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
National Bureau of Standards Metric Kit
Pamphlet issued by the United States National Bureau of Standards discussing the Metric Conversion Act of 1975, the work of the U.S.
United States. National Bureau of Standards.
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greenR: An open-source framework for quantifying urban greenness
How do we quantify the levels of greenness within urban street networks? Numerous attempts to quantify this factor have been made through survey methodologies, remote sensing data, and street view imagery. The results are promising, but are often limited
Sachit Mahajan
doaj +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source

