Results 101 to 110 of about 1,076,377 (343)

The context, influences and challenges for undergraduate nurse clinical education: Continuing the dialogue [PDF]

open access: yes, 2015
Introduction – Approaches to clinical education are highly diverse and becoming increasingly complex to sustain in complex milieu Objective – To identify the influences and challenges of providing nurse clinical education in the undergraduate setting ...
AIHW   +66 more
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Grey Literature '99, October 4-5, 1999

open access: yesIssues in Science and Technology Librarianship, 1999
The article summarizes the Grey Literature '99 Conference, held at the Kellogg Conference Center on the campus of Gallaudet University in Washington, DC. 
Patricia T. Viele
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Excellence in teaching and learning: A review of the literature for the Higher Education Academy [PDF]

open access: yes, 2007
The Higher Education Academy commissioned a review of the literature on excellence in learning and teaching in higher education to enhance the higher education sector’s understanding of the varied conceptualisations and usages of the term ‘excellence ...
Little, Brenda   +3 more
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Grey Literature in European Commission Projects

open access: yes, 2013
The survey is focused on the documentation produced by the European Commission (EC) projects involved in the Framework Programme for Research and Technological Development (hereafter FP7) and managed by the Italian National Research Council (hereafter CNR).
Goggi S   +3 more
openaire   +7 more sources

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