Results 101 to 110 of about 738,461 (306)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Grey literature in France : the GRISELI program [PDF]

open access: yes, 1996
The GRISELI Program is a national information system on grey literature which was set up in France in 1994 by the French Research and Higher Education Ministry within its scientific and technical information and libraries directorate.
GreyNet, Grey Literature Network Service   +1 more
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Grey Literature : The State of the Marketplace [PDF]

open access: yes, 1996
Access to the grey literature of the Soviet Union and its satellites is becoming even more difficult as the information infrastructure continues to dissolve and reorganise on a considerably lesser scale.
GreyNet, Grey Literature Network Service   +1 more
core  

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

Grey Literature Sources in Historical Perspective: Content Analysis of Handwritten Notes [PDF]

open access: yes, 2016
This paper describes historical perspective of grey literature in comparison to the postulates of Serbian enlightenment in the 18th century. The theoretical part of this paper describes comparative analysis between main postulates of grey literature ...
GreyNet, Grey Literature Network Service   +1 more
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Grey literature : the challenges for an increasingly important body of research literature [PDF]

open access: yes, 1996
Grey literature both exemplifies and magnifies the many problems faced by the world's research libraries, which must cope with a rising tide of publications, whether traditional or otherwise, and with the growing expectations of their users and funders ...
Simpson, Donald B. (CRL)   +1 more
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Think Tanks, Twitter, and Grey Literature [PDF]

open access: yes, 2015
This poster aims to track the use of twitter among think tanks and the dissemination of grey literature. Making connections between the future of the online world and knowledge communication to drive change and share resources.Includes: Conference ...
Aloia, Danielle (NYAM)   +1 more
core  

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