Results 41 to 50 of about 247,646 (300)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Evaluating Natural Language Processing and Named Entity Recognition for Bioarchaeological Data Reuse
HeritageBioarchaeology continues to generate growing volumes of data from finite and often destructively sampled resources, making data reusability critical according to FAIR principles (Findable, Accessible, Interoperable, Reusable) and CARE (Collective Benefit,
Alphaeus Lien-Talks
doaj +1 more source
“Grey Literature” in Electronic Archives
Digital Presentation and Preservation of Cultural and Scientific Heritage, 2018 The term „grey literature“ is used for documents disseminated through non-traditional channels. As a general rule, these documents are accessible outside the book publishing and distribution system.
Elena Pavlovska
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
A Systematic Mapping of Grey Literature on K–12 School Acoustic Design
BuildingsClassroom acoustic conditions significantly affect students’ learning outcomes and teachers’ occupational health, yet a systematic gap persists between optimal acoustic standards established in research and their implementation in practice. Although peer-
Xuanwei He +4 more
doaj +1 more source
Environmental Archaeology, Progress and Challenges
Internet Archaeology, 2019 This article explores how the discipline of environmental archaeology has fared over the past 15 years, reflecting on several themes considered by authors in Environmental Archaeology: Meaning and Purpose (Albarella 2001).
Andy J. Howard
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Categorising the Past: lessons from the archaeological resource assessment for Yorkshire
Internet Archaeology, 2007 This article will consider the implications of the Yorkshire regional assessment for how we categorise, analyse and synthesise the past. It argues that we must transcend the existing frameworks, especially their chronological elements, if we are to fully
Steve Roskams, Mark Whyman
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source