Results 41 to 50 of about 6,951,678 (305)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Earthworm occurrence dataset extracted from Russian-language literature [PDF]

open access: yesBiodiversity Data Journal
Earthworms are one of the most important components of temperate ecosystems and groups of soil animals globally, but data on their distribution around the world are still incomplete and uneven.
Maxim Shashkov   +2 more
doaj   +3 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

From grey literature to peer-reviewed evidence: bridging the monitoring gap of nature-based solutions for Kenya’s water resources

open access: yesFrontiers in Environmental Science
Nature-based solutions (NbS) are increasingly adopted across Africa to address water security challenges and biodiversity conservation and offer sustainable alternatives to traditional grey infrastructure.
Cornelius Okello   +8 more
doaj   +1 more source

Antibiotic resistance in primary care in Austria - a systematic review of scientific and grey literature

open access: yesBMC Infectious Diseases, 2011
Background Antibiotic resistance is an increasing challenge for health care services worldwide. While up to 90% of antibiotics are being prescribed in the outpatient sector recommendations for the treatment of community-acquired infections are usually ...
Hoffmann Kathryn   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Guidelines for the production of scientific and technical reports : how to write and distribute grey literature - Version 1.0 [PDF]

open access: yes, 2006
In an effort to enhance quality and standardization in the production of Grey Literature, members of the Istituto Superiore di Sanità (ISS) in Rome, Italy prepared the initial draft of these Guidelines referred to as the "Nancy Style".
GLISC, Grey Literature International Steering Committee
core   +1 more source

Evaluating Natural Language Processing and Named Entity Recognition for Bioarchaeological Data Reuse

open access: yesHeritage
Bioarchaeology continues to generate growing volumes of data from finite and often destructively sampled resources, making data reusability critical according to FAIR principles (Findable, Accessible, Interoperable, Reusable) and CARE (Collective Benefit,
Alphaeus Lien-Talks
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

A Systematic Mapping of Grey Literature on K–12 School Acoustic Design

open access: yesBuildings
Classroom acoustic conditions significantly affect students’ learning outcomes and teachers’ occupational health, yet a systematic gap persists between optimal acoustic standards established in research and their implementation in practice. Although peer-
Xuanwei He   +4 more
doaj   +1 more source

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