Results 41 to 50 of about 7,308,728 (305)

A Whiter Shade of Grey: A new approach to archaeological grey literature using the XML version of the TEI Guidelines

Internet Archaeology, 2005
This article has arisen through the author's interest in two contemporary issues within archaeology: the production and dissemination of grey literature and the potential of XML. Grey literature is examined, with specific reference to unpublished reports
Gail Falkingham
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Using Text Mining to Search for Neolithic Vlaardingen Culture Sites in the Rhine-Meuse-Scheldt Delta

Journal of Computer Applications in Archaeology
This paper presents a study on Vlaardingen Culture (3400–2500 BCE) sites in the Rhine-Meuse-Scheldt delta using AGNES, an intelligent search engine for Dutch and Flemish archaeological grey literature. The aims of this paper are twofold: 1) to provide an
Lasse Van den Dikkenberg, Alex Brandsen
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Towards a Prague Definition of Grey Literature

, 2010
The most common definition of grey literature, the so-called "Luxembourg definition", was discussed and approved during the 3rd International Conference on Grey Literature in 1997.
GreyNet, Grey Literature Network Service, Schopfel, Joachim (University of Lille)   +1 more
core   +1 more source

A terminology-based Re-definition of Grey Literature

, 2010
The conventionally accepted definition of Grey Literature, as Information produced and distributed by non-commercial publishing, does not take into consideration either the increasing availability of forms of grey knowledge, or the growing importance of ...
Pardelli, Gabriella, Marzi, Claudia, Sassi, Manuela   +2 more
core   +1 more source

C.A.R.E. To Challenge Stigma? A Directed Qualitative Content Analysis of Division I Mental Health Webpages

Journal of Intercollegiate Sport
Stigma surrounding mental health in sports is common and damaging. It often prevents athletes from seeking help, as athletes may feel fear of being judged or perceived as weak by teammates, coaches, and administrators when disclosing they may need help ...
Tyler Williams, Lauren Beasley, Beth Ciafrone, Joycelyn Kennedy   +3 more
doaj   +1 more source