Results 41 to 50 of about 1,361,221 (313)
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
The Collaborative Semantic Grid
, 2006 Grid and Semantic Web technologies both enable heterogeneous resources to be joined up to achieve new functionality and capability, and their combined effectiveness has been demonstrated through a number of ‘Semantic Grid’ projects. These typically apply
De Roure, David +7 more
core +1 more source
Simplified numerical approach for incremental sheet metal forming process [PDF]
, 2014 The current work presents a finite element approach for numerical simulation of the incremental sheet metal forming (ISF) process, called here ‘‘ISF-SAM’’ (for ISF-Simplified Analysis Modelling).
BATOZ, Jean-Louis +4 more
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
User oriented access to secure biomedical resources through the grid [PDF]
, 2006 The life science domain is typified by heterogeneous data sets that are evolving at an exponential rate. Numerous post-genomic databases and areas of post-genomic life science research have been established and are being actively explored. Whilst many of
Watt, J +9 more
core
Electrical Engineering and EnergyIn recent years, interest in integration of renewable energy (RE) sources (particularly Wind Energy Systems - WES) into the electrical grid for sustainable, innovative solutions and a greener future continues to grow exponentially.
Fatih Burak, Hulusi Karaca
doaj +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Grid Global Behavior Prediction
, 2011 Complexity has always been one of the most important issues in distributed computing. From the first clusters to grid and now cloud computing, dealing correctly and efficiently with system complexity is the key to taking technology a step further.
Montes, Jesús +5 more
core +1 more source
Impact of Grid Forming Power Converters on the Provision of Grid Services through VSC-HVdc Systems [PDF]
, 2021 High Voltage dc (HVdc) transmission systems have gained increased popularity as a flexible and efficient power transmission option with higher grid controllability.
Marco Liserre +5 more
core +1 more source