Results 51 to 60 of about 322,332 (345)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Grid-Following and Grid-Forming Control in Power Electronic Based Power Systems: A Comparative Study [PDF]

, 2021
The stability of frequency is at risk with increasing penetration of power electronic converters. In this case, the power grid will lack the moment of inertia to maintain a stable voltage and frequency in the event of a large disturbance.
Anvari-Moghaddam, Amjad; id_orcid, Dao Zhou, Amjad Anvari-Moghaddam, Zhou, Dao; id_orcid, Gao, Xian, Xian Gao, Blaabjerg, Frede; id_orcid, Frede Blaabjerg   +7 more
core   +1 more source

Reduced-Order Modeling and Stability Analysis of Grid-Following and Grid-Forming Hybrid Renewable Energy Plants

Energies
The control methods of energy systems can be categorized into grid-following and grid-forming types. The grid-following control method relies on grid synchronization and is prone to stability issues in weak grid conditions.
Yue Ma, Ning Chen, Luming Ge
doaj   +1 more source

A Comparative Study of Grid-Following and Grid-Forming Control Schemes in Power Electronic-Based Power Systems

Power Electronics and Drives, 2023
Along with de-carbonisation, the penetration of power electronic converters has increased, and the power system has become a power electronic-based power system. In such a situation, the stability of the power system faces great challenges.
Gao Xian, Zhou Dao, Anvari-Moghaddam Amjad, Blaabjerg Frede   +3 more
doaj   +1 more source

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur, Faruk Kaya, Bora Derin, Mustafa Lütfi Öveçoğlu, Ju Li, Duygu Ağaoğulları   +5 more
wiley   +1 more source

AC-Side Impedance-Based Stability Assessment in Grid-Forming Modular Multilevel Converters

IEEE Access
Grid-forming converters can emulate the behavior of a synchronous generator through frequency droop control. The stability of grid-forming modular multilevel converters can be studied via the impedance-based stability criterion. This paper presents an ac-
Mehrdad Nahalparvari, Mohsen Asoodar, Staffan Norrga, Hans-Peter Nee   +3 more
doaj   +1 more source

Characterization of Defect Distribution in an Additively Manufactured AlSi10Mg as a Function of Processing Parameters and Correlations with Extreme Value Statistics

Advanced Engineering Materials, EarlyView.
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt, Varma Kvvssn, Hossein Laieghi, Zia Uddin, Peyman Ansari, E. Kıvanç Sadak, Can Barış Toprak, Hüseyin Kızıl, Enrico Salvati   +8 more
wiley   +1 more source

Immunity of Grid-Forming Control Without Energy Storage to Transient Changes of Grid Frequency and Phase

IEEE Open Journal of the Industrial Electronics Society
European grid operators in ENTSO-E and others with a significant amount of inverter-based generation are experiencing a reduction in system inertia and short-circuit power.
Norbert R. Klaes, Jens Fortmann
doaj   +1 more source

Prediction of Surface Topography Parameters in Direct Laser Interference Patterning of Stainless Steel Using Infrared Monitoring and Convolutional Neural Networks

Advanced Engineering Materials, EarlyView.
This study presents an infrared monitoring approach for direct laser interference patterning (DLIP) combined with a convolutional neural network (CNN). Thermal emission data captured during structuring are used to predict surface topography parameters.
Lukas Olawsky, Marcelo Sallese, Leander Kläber, Clemens Kuhn, Keming Du, Andrés Fabián Lasagni   +5 more
wiley   +1 more source