Results 111 to 120 of about 8,482 (293)

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source

Developing and Evaluating the Operating Region of a Grid-Connected Current Source Inverter from Its Mathematical Model

Mathematics
Grid-connected power inverters are indispensable in modern electrical systems, playing a pivotal role in enhancing the integration of renewable energies into power grids.
Carlos R. Baier, Pedro E. Melin, Miguel A. Torres, Roberto O. Ramirez, Carlos Muñoz, Agustin Quinteros   +5 more
doaj   +1 more source

Effect of Alkyl Chain Length on the Bandgap, Ferroelectric, and Photoelectric Properties of Lead‐Based Molecular Ferroelectrics

Advanced Science, EarlyView.
This study develops a novel 2D molecular ferroelectric [C6N2H18]PbI4 with polarization enhanced photovoltaics. It systematically investigates the effect of alkylamine spacer cation chain lengths on the band gap, ferroelectric, and photoelectric properties, offering new design strategies.
Ganghua Zhang, Jinrong Wen, Ping Chen, Zhibo Chen, Pingying Tang, Dezeng Li, Jingshan Hou, Yongzheng Fang   +7 more
wiley   +1 more source

Real-time simulation comparison of the impact of inertia on grid following and grid forming inverter IGBT lifetime

Results in Engineering
This study examines the thermal effects on Insulated Gate Bipolar Transistors (IGBTs) in Grid-Following (GFL) and Grid-Forming (GFM) inverters under Virtual Synchronous Generator (VSG) inertia control.
Sunjoh Christian Verbe, Keigo Higashiura, Md. Amit Hasan, Ryuto Shigenobu, Akiko Takahashi, Masakazu Ito, Hisao Taoka   +6 more
doaj   +1 more source

Mathematical modeling and advanced control strategies for enhanced voltage and frequency regulation of grid-forming inverters [PDF]

With the rapid increase in renewable energy integration, conventional inverters are finding it difficult to maintain stable voltage and frequency. In contrast, grid-forming inverters actively regulate these parameters, providing enhanced stability and ...
Zhang, Xiyuan
core  

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

Grid-Forming Inverters in Photovoltaic Power Systems: A Comprehensive Review of Modeling, Control, and Stability Perspectives

Energies
Grid-forming inverters (GFIs) are emerging as a key enabling technology for maintaining stability in renewable-dominated power systems, where conventional synchronous generation is progressively displaced by inverter-based resources.
Youness Hakam, Mohamed Tabaa
doaj   +1 more source

Circular RNA circNrip1 Interacts with SYNCRIP to Promote Neuropathic Pain by Stabilizing Tlr2 mRNA in Primary Sensory Neurons

Advanced Science, EarlyView.
Model of circNrip1 (cNrip1) upregulation driving neuropathic pain mechanisms. After peripheral nerve injury, increased FUS triggers the formation and upregulation of cNrip1 in injured DRG neurons. Upregulated cNrip1 recruits SYNCRIP to the 3′‐UTR of Tlr2 mRNA by binding to both, thereby promoting SYNCRIP‐triggered Tlr2 mRNA stability and increasing ...
Xiaozhou Feng, Jifang Xiao, Congcong Huang, Bao‐Chun Jiang, Bing Wang, Xu Li, Shibin Du, Tolga Berkman, Chun‐Hsien Wen, Weihua Cai, Dilip Sharma, Kun Wang, Longfei Ma, Huijuan Hu, Yuan‐Xiang Tao   +14 more
wiley   +1 more source

Insights on Blackstart Provisioning Using a Synchronous Generator and Grid-Forming Inverter Using EMT Simulations

Energies
Grid-forming inverters (GFMIs) have been identified as critical assets in ensuring modern power system reliability. Their ability to synthesize an internal voltage reference while emulating synthetic inertia has sparked extensive research.
Huzaifa Karimjee, Satish Ranade, Deepak Ramasubramanian, Olga Lavrova, Jose Ribeiro   +4 more
doaj   +1 more source

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation

Advanced Science, EarlyView.
High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott, Georgeos Hardo, Ruizhe Li, Jack Bradley, Ashraf Zarkan, Somenath Bakshi   +5 more
wiley   +1 more source